Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 2/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | ADA | P00813 | 6/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714348 | 0.89 | KDM5B (0.54) | CA5AKDM5AKDM5BKDM4AKDM4C | |
| SCHEMBL9714146 | 0.85 | CA5A (0.58) | CA5AKDM5AKDM5BKDM4AKDM4C | |
| SCHEMBL10567701 | 0.81 | CYP1A2 (0.43) | KDM5AKDM5BKDM4AKDM4C | |
| SCHEMBL9714457 | 0.78 | GRM2 (0.43) | CA5AKDM5AKDM5BKDM4AKDM4C | |
| SCHEMBL9714527 | 0.78 | GRM2 (0.43) | KDM5AKDM5BKDM4AKDM4CAURKA | |
| SCHEMBL9714504 | 0.78 | CYP11B1 (0.47) | KDM5AKDM5BKDM4AKDM4CAURKA | |
| SCHEMBL9714098 | 0.78 | LMNA (0.50) | KDM5AKDM5BKDM4CADA | |
| SCHEMBL9857834 | 0.76 | CA5A (0.73) | CA5AAURKAPDPK1RPS6KB1GRM2 | |
| SCHEMBL15965384 | 0.76 | KDM4C (0.57) | KDM4CAURKARPS6KB1ADAGRM2 | |
| SCHEMBL9714533 | 0.74 | GRM2 (0.48) | KDM5AKDM5BKDM4AKDM4CAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248414-B1 | ARALKYL IMIDAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-23 | — | — | EP | disclosed |
| US-4851424-A | 1-Phenyl-lower alkyl-imidazole 4- or 5-carboxamide compounds which are useful in the treatment of epilepsy | CIBA-GEIGY CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0248414-A2 | Aralkyl imidazole derivatives | CIBA-GEIGY AG (CH) | 1987-12-09 | — | — | EP | disclosed |