Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30587480 | 0.87 | KDM4C (0.47) | GRM2KDM4CVNN1KDM4AKDM5A | |
| SCHEMBL18365944 | 0.87 | KDM4C (0.47) | GRM2KDM4CVNN1KDM4AKDM5A | |
| SCHEMBL19659010 | 0.86 | MAOA (0.44) | GRM2ALDH1A1KDM4CKDM4AKDM5A | |
| SCHEMBL10570402 | 0.83 | GRM2 (0.56) | GRM2VNN1KDM5AKDM5BCACNA1G | |
| SCHEMBL30587512 | 0.83 | GRM2 (0.56) | GRM2VNN1KDM5AKDM5BCACNA1G | |
| SCHEMBL15965384 | 0.82 | KDM4C (0.57) | GRM2ALDH1A1KDM4CAURKARPS6KB1 | |
| SCHEMBL30587618 | 0.81 | ALDH1A1 (0.47) | GRM2ALDH1A1HTT | |
| SCHEMBL9714457 | 0.80 | GRM2 (0.43) | GRM2KDM4CKDM4AKDM5AKDM5B | |
| SCHEMBL15965385 | 0.78 | KLKB1 (0.49) | GRM2 | |
| SCHEMBL15964744 | 0.78 | RBP4 (0.54) | KDM4CKDM4AKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248414-B1 | ARALKYL IMIDAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-23 | — | — | EP | disclosed |
| US-4851424-A | 1-Phenyl-lower alkyl-imidazole 4- or 5-carboxamide compounds which are useful in the treatment of epilepsy | CIBA-GEIGY CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0248414-A2 | Aralkyl imidazole derivatives | CIBA-GEIGY AG (CH) | 1987-12-09 | — | — | EP | disclosed |