Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714816 | 0.80 | SLC6A2 (0.34) | MAOB | |
| SCHEMBL9714646 | 0.78 | MEN1 (0.35) | — | |
| SCHEMBL9714665 | 0.76 | SGMS2 (0.39) | MAOB | |
| Hydrochloric Acid SCHEMBL9714685 | 0.76 | MAOB (0.36) | MAOB | |
| SCHEMBL9714823 | 0.75 | MAOA (0.35) | MAOB | |
| SCHEMBL9714779 | 0.75 | CYP3A4 (0.33) | MAOB | |
| SCHEMBL9714712 | 0.73 | TSHR (0.36) | MAOB | |
| SCHEMBL9714488 | 0.72 | CYP3A4 (0.36) | MAOB | |
| SCHEMBL9714829 | 0.70 | CYP3A4 (0.34) | — | |
| SCHEMBL9714754 | 0.70 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166210-A | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5028615-A | Treatment of hypersensitivity | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-07-02 | — | — | US | disclosed |
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |