Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715039 | 0.89 | LMNA (0.42) | P2RX7POLBRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9715021 | 0.86 | PTGDR2 (0.39) | NPY5RRAB9AMAPTNPC1NR1I2 | |
| Hydrochloric Acid SCHEMBL9715064 | 0.85 | PTGDR2 (0.39) | NPY5RRAB9AMAPTNPC1NR1I2 | |
| SCHEMBL9715049 | 0.81 | RAB9A (0.54) | POLBRAB9AMAPTSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL9714965 | 0.80 | RAB9A (0.53) | POLBRAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9715038 | 0.77 | L3MBTL1 (0.43) | POLBRAB9ASMN1; SMN2KDM4EPTGS2 | |
| Hydrochloric Acid SCHEMBL9714943 | 0.76 | L3MBTL1 (0.45) | POLBRAB9ASMN1; SMN2KDM4EPTGS2 | |
| Hydrochloric Acid SCHEMBL9714930 | 0.73 | LMNA (0.41) | POLBMAPTKDM4E | |
| SCHEMBL8514273 | 0.68 | P2RX7 (0.47) | P2RX7POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12809523 | 0.67 | POLB (0.61) | POLBRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057534-A | Anxiolytic, anticonfulsant and muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | claimed |
| WO-1992018484-A1 | 3-AMINO-5-ARYLPYRAZOLE-4-ACETIC ACID DERIVATIVES EXHIBITING THERAPEUTIC EFFECTS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-10-29 | — | — | WO | disclosed |
| US-5057534-A | Anxiolytic, anticonfulsant and muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-10-15 | — | — | US | disclosed |