Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9715248 | 0.76 | CCR5 (0.36) | GNAI3GNAO1GNAI1CCR5KCNH2 | |
| Hydrochloric Acid SCHEMBL11786483 | 0.76 | CCR5 (0.36) | GNAI3GNAO1GNAI1CCR5KCNH2 | |
| SCHEMBL2266931 | 0.74 | KCNH2 (0.35) | GNAI3GNAO1GNAI1CCR5KCNH2 | |
| SCHEMBL2267102 | 0.74 | KCNH2 (0.35) | GNAI3GNAO1GNAI1CCR5KCNH2 | |
| Water SCHEMBL2392672 | 0.72 | ALDH1A1 (0.36) | GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL9242727 | 0.72 | GNAI3 (0.32) | GNAI3GNAO1GNAI1 | |
| Iodide SCHEMBL11780477 | 0.72 | KCNH2 (0.34) | GNAI3GNAO1GNAI1CCR5KCNH2 | |
| Iodide SCHEMBL11780008 | 0.72 | KCNH2 (0.34) | GNAI3GNAO1GNAI1CCR5KCNH2 | |
| Water SCHEMBL2392678 | 0.71 | — | — | |
| SCHEMBL18556293 | 0.65 | CCR5 (0.38) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535477-B1 | Process for the recovery of hydrocarbons from a hydrocarbon rich gel | CASSELLA FARBWERKE MAINKUR AG (DE) | 1995-07-26 | — | — | EP | claimed |
| US-5276248-A | Adding surfactants to form gel in water and storage | CASSELLA AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| EP-0535477-A1 | Process for the recovery of hydrocarbons from a hydrocarbon rich gel | CASSELLA Aktiengesellschaft (DE) | 1993-04-07 | — | — | EP | claimed |
| EP-0888903-B1 | Image-receptor sheet containing a foam layer for an image-recording process | SCHOELLER FELIX JUN FOTO (DE) | 2001-01-03 | — | — | EP | disclosed |
| US-6156420-A | Support material for image-recording processes | FELIX SCHOELLER JR. FOTO-UND SPEZIALPAPIERE GMBH & CO. KG (DE) | 2000-12-05 | — | — | US | disclosed |
| EP-0888903-A2 | Image-receptor sheet containing a foam layer for an image-recording process | Felix Schoeller jr Foto- und Spezialpapiere GmbH & Co. KG (DE) | 1999-01-07 | — | — | EP | disclosed |
| EP-0535477-B1 | Process for the recovery of hydrocarbons from a hydrocarbon rich gel | CASSELLA FARBWERKE MAINKUR AG (DE) | 1995-07-26 | — | — | EP | disclosed |
| EP-0531807-B1 | Process for storing and transporting liquid hydrocarbons | CASSELLA FARBWERKE MAINKUR AG (DE) | 1995-03-15 | — | — | EP | disclosed |
| US-5276248-A | Adding surfactants to form gel in water and storage | CASSELLA AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| US-5276247-A | Contains cationic or anionic surfactants; treating with laminar mineral | CASSELLA AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0535477-A1 | Process for the recovery of hydrocarbons from a hydrocarbon rich gel | CASSELLA Aktiengesellschaft (DE) | 1993-04-07 | — | — | EP | disclosed |
| EP-0531807-A1 | Process for storing and transporting liquid hydrocarbons | CASSELLA Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |