SCHEMBL9715751

SCHEMBL9715751

C=C(c1ccccc1C(C)C(=O)O)c1cccc(C(=O)OC)c1C(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.42
PTGS2 P35354 2/20 0.42
KDM4E B2RXH2 3/20 0.41
KMT2A Q03164 3/20 0.41
ATM Q13315 2/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 3/20 0.41
LMNA P02545 1/20 0.41
CXCL8 P10145 1/20 0.40
ALDH1A1 P00352 2/20 0.40
CFTR P13569 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10399525 0.90 TSHR (0.46) KDM4EKMT2ATSHRALDH1A1HSD17B10
SCHEMBL9715759 0.89 TSHR (0.45) PTGS1PTGS2KDM4EKMT2AATM
SCHEMBL11419763 0.86 KDM4E (0.47) PTGS1PTGS2KDM4EKMT2AATM
SCHEMBL2439694 0.84 TSHR (0.52) PTGS1PTGS2KDM4EKMT2AATM
SCHEMBL9717407 0.83 KDM4E (0.41) KDM4EKMT2AATMGAATSHR
SCHEMBL9715714 0.78 ALDH1A1 (0.47) PTGS1PTGS2KDM4EKMT2AGAA
SCHEMBL9715754 0.77 PTGS1 (0.52) PTGS1PTGS2KDM4EKMT2AALDH1A1
SCHEMBL9715755 0.77 PTGS2 (0.44) PTGS1PTGS2KDM4EKMT2ATSHR
SCHEMBL9632497 0.76 PTGS2 (0.47) PTGS1PTGS2KDM4EKMT2AATM
SCHEMBL9715765 0.76 PTGS2 (0.40) PTGS1PTGS2KDM4EKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0304495-B1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-05-27 EP disclosed