Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601528 | 0.84 | GABRA1 (0.41) | PTGS2PTGS1KMT2ACYP3A4LMNA | |
| SCHEMBL9715714 | 0.81 | ALDH1A1 (0.47) | PTGS2PTGS1KMT2AAKR1C3NAPRT | |
| SCHEMBL2035096 | 0.81 | CXCL8 (0.46) | PTGS2PTGS1KMT2ACYP3A4LMNA | |
| SCHEMBL9715755 | 0.80 | PTGS2 (0.44) | PTGS2PTGS1KMT2ALMNAMEN1 | |
| SCHEMBL9715767 | 0.80 | PTGS1 (0.43) | PTGS2PTGS1KMT2ALMNAMEN1 | |
| SCHEMBL9632497 | 0.80 | PTGS2 (0.47) | PTGS2PTGS1KMT2ACYP3A4LMNA | |
| SCHEMBL9717372 | 0.79 | LMNA (0.34) | PTGS2PTGS1KMT2ACYP3A4LMNA | |
| SCHEMBL9715718 | 0.79 | CXCL8 (0.41) | PTGS2PTGS1AKR1C3AKR1C2CXCL8 | |
| SCHEMBL9715759 | 0.78 | TSHR (0.45) | PTGS2PTGS1KMT2ALMNATDP1 | |
| SCHEMBL9715754 | 0.78 | PTGS1 (0.52) | PTGS2PTGS1KMT2AAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304495-B1 | PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4908473-A | Reacting a (1-arylethenyl)vinylbenzene with carbon monoxide and water or alcohol in the presence of carbonylation catalyst | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-03-13 | — | — | US | disclosed |