Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715766 | 0.89 | KMT2A (0.50) | PTGS1PTGS2HPGDALDH1A1KMT2A | |
| SCHEMBL9715715 | 0.87 | HCRTR1 (0.48) | PTGS1PTGS2ALDH1A1KMT2AKCNK3 | |
| SCHEMBL8473051 | 0.84 | PTGS2 (0.64) | PTGS1PTGS2HPGDALDH1A1KMT2A | |
| SCHEMBL7885098 | 0.84 | PTGS2 (0.64) | PTGS1PTGS2HPGDALDH1A1KMT2A | |
| SCHEMBL362211 | 0.84 | PTGS2 (0.64) | PTGS1PTGS2HPGDALDH1A1KMT2A | |
| SCHEMBL9715714 | 0.83 | ALDH1A1 (0.47) | PTGS1PTGS2HPGDALDH1A1KMT2A | |
| SCHEMBL9715759 | 0.82 | TSHR (0.45) | PTGS1PTGS2HPGDALDH1A1KMT2A | |
| SCHEMBL9715755 | 0.81 | PTGS2 (0.44) | PTGS1PTGS2HPGDALDH1A1KMT2A | |
| SCHEMBL9632497 | 0.81 | PTGS2 (0.47) | PTGS1PTGS2HPGDALDH1A1KMT2A | |
| SCHEMBL9715718 | 0.80 | CXCL8 (0.41) | PTGS1PTGS2ALDH1A1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304495-B1 | PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-4908473-A | Reacting a (1-arylethenyl)vinylbenzene with carbon monoxide and water or alcohol in the presence of carbonylation catalyst | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-03-13 | — | — | US | disclosed |
| EP-0304495-A1 | PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-03-01 | — | — | EP | disclosed |