SCHEMBL9715859

SCHEMBL9715859

C=CCCc1ccccc1[SiH2]Cl

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715821 0.86 TDP1 (0.42) TLR8
SCHEMBL9715832 0.86 TDP1 (0.42) TLR8
SCHEMBL9715878 0.86 TDP1 (0.42) TLR8
SCHEMBL15848026 0.81 GABRA1 (0.32) TLR8
SCHEMBL3850180 0.80 GABRA1 (0.42)
SCHEMBL3481942 0.74 HTR1A (0.36)
SCHEMBL248652 0.74 TAAR1 (0.54)
SCHEMBL7563209 0.74 TAAR1 (0.56)
SCHEMBL31297415 0.74 ALDH1A1 (0.35) TLR8
SCHEMBL11186151 0.71 TLR8 (0.34) TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344735-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device DOW CORNING TORAY CO., LTD. (JP) 2015-12-03 US disclosed
WO-2014104388-A2 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-07-03 WO disclosed
US-5098981-A POLYORGANOSILOXANE CHISSO CORPORATION (JP) 1992-03-24 US disclosed
EP-0349920-A2 Polyorganosiloxane Chisso Corporation (JP) 1990-01-10 EP disclosed