Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.91 |
| ▸ | HPGD | P15428 | 6/20 | 0.91 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.91 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL6249450 | 0.97 | KDM4E (0.95) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL11599872 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL2511998 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL6934680 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL458273 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL11514957 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL9981 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL3132735 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL1026592 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 | |
| Salicylic Acid SCHEMBL12477385 | 0.95 | KDM4E (0.91) | KDM4EHPGDALDH1A1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236569-A1 | Lead-free Ballistic Modifier for Rocket Motor Propellants | USA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2025-07-24 | — | — | US | claimed |
| CN-114230194-B | Rare earth-based ultraviolet shielding coated glass | 中稀产业发展(天津)集团有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-114230194-A | Rare earth-based ultraviolet shielding type coated glass | 中稀产业发展(天津)集团有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-112980206-A | Flame-retardant wear-resistant foamed asphalt and preparation method thereof | 毛佳耀 | 2021-06-18 | — | — | CN | claimed |
| CN-109337246-B | Environment-friendly high-weather-resistance PVC (polyvinyl chloride) profile particle and processing technology thereof | 广东江顺新材料科技股份有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-111621118-A | ABS composite material for manufacturing 5G fiber distribution box and preparation method thereof | 珠海光林新材料科技有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-106957695-B | Modifier for preparing supercritical carbon dioxide leaching coal slurry fuel and application thereof | 长沙紫宸科技开发有限公司 | 2020-06-09 | — | — | CN | claimed |
| EP-2443204-B1 | COATING COMPOSITIONS INCLUDING CERAMIC PARTICLES | AIRBUS SAS (FR) | 2019-08-07 | — | — | EP | claimed |
| US-20130185990-A1 | Combustion Modifier and Method for Improving Fuel Combustion | PERRY STEPHEN C (US) | 2013-07-25 | — | — | US | claimed |
| EP-2443204-A1 | COATING COMPOSITIONS INCLUDING CERAMIC PARTICLES | European Aeronautic Defence And Space Company Eads France (FR) | 2012-04-25 | — | — | EP | claimed |
| US-20120085261-A1 | CERAMIC PARTICLES AND COATING COMPOSITIONS INCLUDING SAID PARTICLES | AIRBUS GROUP SAS (FR) | 2012-04-12 | — | — | US | claimed |
| US-7901472-B2 | Combustion modifier and method for improving fuel combustion | CONSEAL INTERNATIONAL INCORPORATED (US) | 2011-03-08 | — | — | US | claimed |
| US-20110021396-A1 | Fuel additive | PERRY STEPHEN C | 2011-01-27 | — | — | US | claimed |
| WO-2010146001-A1 | COATING COMPOSITIONS INCLUDING CERAMIC PARTICLES | EUROPEAN AERONAUTIC DEFENCE AND SPACE COMPANY EADS FRANCE (FR) | 2010-12-23 | — | — | WO | claimed |
| US-20090056207-A1 | Fuel conditioner and method for improving fuel combustion | CONSEAL INTERNATIONAL INCORPORATED | 2009-03-05 | — | — | US | claimed |
| US-7291217-B2 | Non-toxic corrosion-protection pigments based on rare earth elements | UNIVERSITY OF DAYTON (US) | 2007-11-06 | — | — | US | claimed |
| US-20040104377-A1 | Non-toxic corrosion-protection pigments based on rare earth elements | UNIVERSITY OF DAYTON | 2004-06-03 | — | — | US | claimed |
| US-20040020568-A1 | Non-toxic corrosion-protection conversion coats based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-02-05 | — | — | US | claimed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | claimed |
| EP-4545591-B1 | CROSSLINKABLE POLYETHYLENE BLEND, PREPARATION METHOD AND USE THEREOF | WUHU MIDEA SMART KITCHEN APPLIANCE MFG CO LTD (CN) | 2026-02-18 | — | — | EP | disclosed |
| US-20250236569-A1 | Lead-free Ballistic Modifier for Rocket Motor Propellants | USA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2025-07-24 | — | — | US | disclosed |
| CN-114746390-B | Storage and transport stabilizers for polymerizable compounds | 巴斯夫欧洲公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4545591-A1 | CROSSLINKABLE POLYETHYLENE BLEND, PREPARATION METHOD AND USE THEREOF | Wuhu Midea Smart Kitchen Appliance Manufacturing Co., Ltd. (CN) | 2025-04-30 | — | — | EP | disclosed |
| CN-119899451-A | Crosslinkable polyethylene blend, and preparation method and application thereof | 芜湖美的智能厨电制造有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-118006059-A | Oxidation-resistant seven-hole plum blossom honeycomb tube and preparation method thereof | 安庆市悦发管业有限公司 | 2024-05-10 | — | — | CN | disclosed |
| US-20230348694-A1 | SHELF LIFE- AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS | BASF SE (DE) | 2023-11-02 | — | — | US | disclosed |
| CN-114230194-B | Rare earth-based ultraviolet shielding coated glass | 中稀产业发展(天津)集团有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-114746390-A | Storage and transport stabilizers for polymerizable compounds | 巴斯夫欧洲公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114230194-A | Rare earth-based ultraviolet shielding type coated glass | 中稀产业发展(天津)集团有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-110819149-B | Preparation method of fibrous rare earth antirust pigment | 南昌航空大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-111647300-B | Preparation method of antirust pigment slurry for cathode electrophoretic coating | 南昌航空大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-112980206-A | Flame-retardant wear-resistant foamed asphalt and preparation method thereof | 毛佳耀 | 2021-06-18 | — | — | CN | disclosed |
| CN-109337246-B | Environment-friendly high-weather-resistance PVC (polyvinyl chloride) profile particle and processing technology thereof | 广东江顺新材料科技股份有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112457522-A | Environment-friendly efficient dust-free composite heat stabilizer and preparation method thereof | 威海市建平塑业股份有限公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-111647300-A | Anti-rust pigment for cathode electrophoretic coating and preparation method of slurry of anti-rust pigment | 南昌航空大学 | 2020-09-11 | — | — | CN | disclosed |
| CN-111621118-A | ABS composite material for manufacturing 5G fiber distribution box and preparation method thereof | 珠海光林新材料科技有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-106957695-B | Modifier for preparing supercritical carbon dioxide leaching coal slurry fuel and application thereof | 长沙紫宸科技开发有限公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-110819149-A | Fibrous rare earth antirust pigment and preparation method thereof | 南昌航空大学 | 2020-02-21 | — | — | CN | disclosed |
| EP-2443204-B1 | COATING COMPOSITIONS INCLUDING CERAMIC PARTICLES | AIRBUS SAS (FR) | 2019-08-07 | — | — | EP | disclosed |
| US-10227525-B2 | Rare earth materials to enhance properties of ceramic particles | BAKER HUGHES, A GE COMPANY, LLC (US) | 2019-03-12 | — | — | US | disclosed |
| CN-107308186-A | It is used for the biomedical applications and the bismuth mercaptan of other purposes for the treatment of for including bacterial biof iotalm as antiseptic | 微生物公司 | 2017-11-03 | — | — | CN | disclosed |
| WO-2017120275-A1 | RARE EARTH MATERIALS TO ENHANCE PROPERTIES OF CERAMIC PARTICLES | BAKER HUGHES INCORPORATED (US) | 2017-07-13 | — | — | WO | disclosed |
| US-20170190958-A1 | RARE EARTH MATERIALS TO ENHANCE PROPERTIES OF CERAMIC PARTICLES | BAKER HUGHES INCORPORATED (US) | 2017-07-06 | — | — | US | disclosed |
| US-20160332194-A1 | KINETICALLY CONTROLLED SOL-GEL DOPING METHOD | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2016-11-17 | — | — | US | disclosed |
| US-20130185990-A1 | Combustion Modifier and Method for Improving Fuel Combustion | PERRY STEPHEN C (US) | 2013-07-25 | — | — | US | disclosed |
| US-8404202-B2 | Urea-resistant catalytic units and methods of using the same | FORD GLOBAL TECHNOLOGIES, LLC (US) | 2013-03-26 | — | — | US | disclosed |
| US-8323362-B2 | Combustion modifier and method for improving fuel combustion | PERRY STEPHEN C (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120230894-A1 | Urea-Resistant Catalytic Units And Methods of Using The Same | FORD GLOBAL TECHNOLOGIES, LLC (US) | 2012-09-13 | — | — | US | disclosed |
| US-8207084-B2 | Urea-resistant catalytic units and methods of using the same | FORD GLOBAL TECHNOLOGIES, LLC (US) | 2012-06-26 | — | — | US | disclosed |
| EP-2443204-A1 | COATING COMPOSITIONS INCLUDING CERAMIC PARTICLES | European Aeronautic Defence And Space Company Eads France (FR) | 2012-04-25 | — | — | EP | disclosed |
| US-20120085261-A1 | CERAMIC PARTICLES AND COATING COMPOSITIONS INCLUDING SAID PARTICLES | AIRBUS GROUP SAS (FR) | 2012-04-12 | — | — | US | disclosed |
| US-20110154726-A1 | Combustion Modifier and Method for Improving Fuel Combustion | CONSEAL INTERNATIONAL INCORPORATED (US) | 2011-06-30 | — | — | US | disclosed |
| US-20110064633-A1 | Multi-Functional Catalyst Block and Method of Using the Same | FORD GLOBAL TECHNOLOGIES, LLC (US) | 2011-03-17 | — | — | US | disclosed |
| US-7901472-B2 | Combustion modifier and method for improving fuel combustion | CONSEAL INTERNATIONAL INCORPORATED (US) | 2011-03-08 | — | — | US | disclosed |
| US-20110021396-A1 | Fuel additive | PERRY STEPHEN C | 2011-01-27 | — | — | US | disclosed |
| WO-2010146001-A1 | COATING COMPOSITIONS INCLUDING CERAMIC PARTICLES | EUROPEAN AERONAUTIC DEFENCE AND SPACE COMPANY EADS FRANCE (FR) | 2010-12-23 | — | — | WO | disclosed |
| US-20100322833-A1 | Urea-Resistant Catalytic Units and Methods of Using the Same | FORD GLOBAL TECHNOLOGIES, LLC (US) | 2010-12-23 | — | — | US | disclosed |
| US-7772420-B2 | (Meth)acrylic esters of monoalkoxylated polyols, and production thereof | BASF AKTIENGESELLSCHAFT | 2010-08-10 | — | — | US | disclosed |
| US-7687596-B2 | (Meth)acrylic acid esters of alkyoxylated unsaturated polyol ethers, and production thereof | BASF AKTIENGESELLSCHAFT | 2010-03-30 | — | — | US | disclosed |
| US-20090056207-A1 | Fuel conditioner and method for improving fuel combustion | CONSEAL INTERNATIONAL INCORPORATED | 2009-03-05 | — | — | US | disclosed |
| US-7420013-B2 | Mixtures of compounds comprising at least two double bonds and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-02 | — | — | US | disclosed |
| US-7405321-B2 | (Meth)acrylic ester of alkenylene glycols and the use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-29 | — | — | US | disclosed |
| US-7259212-B2 | (Meth)acrylic esters of polyalkoxylated trimethylolpropane | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-21 | — | — | US | disclosed |
| US-7250481-B2 | Reacting polyalcohol with at least one ethylenically unsaturated carboxylic acid in the presence of at least one esterification catalyst and of at least one polymerization inhibitor, polymerizing the reaction mixture, in the presence of at least one radical initiator, postcrosslinking, drying | BASF AKTIENGESELLSCHAFT (DE) | 2007-07-31 | — | — | US | disclosed |
| US-20070129564-A1 | Method for the production of (meth)acrylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
| US-7199211-B2 | (Meth)acrylic esters of polyalkoxylated trimethylolpropane | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-03 | — | — | US | disclosed |
| US-20060247377-A1 | (Meth)acrylic ester of alkenylene glycols and the use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-02 | — | — | US | disclosed |
| US-20060235141-A1 | Mixtures of compounds comprising at least two double bonds and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-19 | — | — | US | disclosed |
| US-20060212011-A1 | Mixtures of polyalkoxylated trimethylolpropane (meth) acrylate | BASF AKTIENGESELLSCHAFT, A GERMAN CORP. (DE) | 2006-09-21 | — | — | US | disclosed |
| US-20060167215-A1 | (Meth)acrylic acid esters of alkoxylated unsaturated polyol ethers, and production thereof | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
| US-20060155057-A1 | (Meth)acrylic esters of monoalkoxylated polyols, and production thereof | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-13 | — | — | US | disclosed |
| US-20060020078-A1 | (Meth) acrylic esters of polyalkoxylated trimethylolpropane | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | US | disclosed |
| US-20050215752-A1 | (Meth)acrylic esters of polyalkoxylated trimethylolpropane | BASF AKTIENGESELLSCHAFT A GERMAN CORPORATION (DE) | 2005-09-29 | — | — | US | disclosed |
| US-20050176910-A1 | Method for the production of esters of polyalcohols | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-11 | — | — | US | disclosed |
| US-20050165208-A1 | free-radical crosslinkers for polymers (superabsorbents); high hydrolysis stability; Acrylic Ester | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-28 | — | — | US | disclosed |
| US-6864213-B2 | Alkaline earth / rare earth lean NOx catalyst | DELPHI TECHNOLOGIES, INC. (US) | 2005-03-08 | — | — | US | disclosed |
| US-20030118824-A1 | Coated silica particles and method for production thereof | AKZO NOBEL N.V. (NL) | 2003-06-26 | — | — | US | disclosed |
| US-20020132725-A1 | Alkaline earth / rare earth lean NOx catalyst | UMICORE AG & CO. KG (DE) | 2002-09-19 | — | — | US | disclosed |
| US-20020132725-A1 | Alkaline earth / rare earth lean NOx catalyst | UMICORE AG & CO. KG (DE) | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020078-A1 | (Meth) acrylic esters of polyalkoxylated trimethylolpropane | ALKBH3, CHRM2, PAM | KDM4E 558/4885HPGD 869/4885ALDH1A1 418/4885 |
| US-20070129564-A1 | Method for the production of (meth)acrylic acid esters | MMAB, ACR, MCCC2 | KDM4E 1237/4885HPGD 223/4885ALDH1A1 291/4885 |
| US-20060212011-A1 | Mixtures of polyalkoxylated trimethylolpropane (meth) acrylate | C9, PAM, C3AR1 | KDM4E 2582/4885HPGD 1659/4885ALDH1A1 463/4885 |
| US-20060247377-A1 | (Meth)acrylic ester of alkenylene glycols and the use thereof | CHRM4, CHRM3, CHRM1 | KDM4E 1870/4885HPGD 1317/4885ALDH1A1 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.