Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | TTR | P02766 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.60 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.60 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28458919 | 0.90 | SMN1; SMN2 (0.49) | KMT2AMEN1HPGDTTRKDM4E | |
| SCHEMBL16919799 | 0.89 | MAPT (0.57) | KMT2AMEN1HPGDTTRKDM4E | |
| SCHEMBL9173435 | 0.85 | KCNA3 (0.56) | MAPTHTR1AMAPK1HTTPTGER1 | |
| SCHEMBL30293150 | 0.85 | TTR (0.75) | KMT2AMEN1HPGDTTRKDM4E | |
| SCHEMBL9149164 | 0.85 | TTR (0.75) | KMT2AMEN1HPGDTTRKDM4E | |
| SCHEMBL16919800 | 0.84 | TTR (0.44) | KMT2AMEN1HPGDTTRKDM4E | |
| SCHEMBL972874 | 0.84 | MEN1 (0.52) | KMT2AMEN1TTRPTGER1RXRA | |
| SCHEMBL9173778 | 0.82 | TTR (0.64) | KMT2AMEN1HPGDTTRKDM4E | |
| SCHEMBL16919801 | 0.82 | KCNA3 (0.46) | TTRMAPTMAPK1PTGER1TDP1 | |
| SCHEMBL3290486 | 0.82 | TTR (0.63) | KMT2AMEN1HPGDTTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015269-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2011-01-20 | — | — | US | claimed |
| CN-108586278-B | Preparation and application of anthraquinone compound for inducing liver cancer paracellular apoptosis | 广西医科大学 | 2020-09-08 | — | — | CN | disclosed |
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2015-07-23 | — | — | US | disclosed |
| US-8324411-B2 | Process for the preparation of DIACEREIN | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2012-12-04 | — | — | US | disclosed |
| US-20110015269-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2011-01-20 | — | — | US | disclosed |
| EP-2234953-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | Laboratorio Chimico Internazionale S.p.A. (IT) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009090483-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203442-A1 | Anthraquinone Analogs and Methods of Making and Using Thereof | PCNA, KRAS, RECQL | KMT2A 1122/4885MEN1 677/4885HPGD 950/4885 |
| US-20110015269-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | ALOX15B, ALOX12, ACAT1 | KMT2A 3332/4885MEN1 1265/4885HPGD 854/4885 |
| US-10544090-B2 | Anthraquinone analogs and methods of making and using thereof | PCNA, KRAS, RECQL | KMT2A 1122/4885MEN1 677/4885HPGD 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.