Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9173435 | 0.86 | KCNA3 (0.56) | MAOBKCNA3ELANEPTGER1PTGER4 | |
| SCHEMBL971641 | 0.84 | KMT2A (0.60) | MEN1KMT2APTGER1RXRARXRB | |
| SCHEMBL16919801 | 0.83 | KCNA3 (0.46) | MAOBKCNA3ELANEPTGER1PTGER4 | |
| SCHEMBL9754264 | 0.82 | KCNA3 (0.63) | MAOBKMT2AKCNA3ELANEPTGER1 | |
| SCHEMBL16072720 | 0.82 | KCNA3 (0.58) | MAOBKCNA3PTGER1PTGER4PTGER3 | |
| SCHEMBL28458919 | 0.81 | SMN1; SMN2 (0.49) | MEN1KMT2AKCNA3PTGER1PTGER4 | |
| SCHEMBL16919799 | 0.81 | MAPT (0.57) | MEN1KMT2APTGER1PTGER4PTGER3 | |
| SCHEMBL8996370 | 0.79 | EGFR (0.58) | MEN1MAOAMAOBEPHX2KMT2A | |
| SCHEMBL21657907 | 0.77 | ALDH1A1 (0.44) | MEN1KMT2APTGER1PTGER4PTGER3 | |
| SCHEMBL21657912 | 0.77 | MEN1 (0.45) | MEN1KMT2APTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324411-B2 | Process for the preparation of DIACEREIN | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2012-12-04 | — | — | US | disclosed |
| US-20110015269-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2011-01-20 | — | — | US | disclosed |
| EP-2234953-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | Laboratorio Chimico Internazionale S.p.A. (IT) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009090483-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015269-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | ALOX15B, ALOX12, ACAT1 | MEN1 1265/4885MAOA 630/4885MAOB 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.