Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706043 | 0.84 | SIGMAR1 (0.43) | IDO1SIGMAR1NPC1RAB9A | |
| SCHEMBL5704258 | 0.81 | TSHR (0.48) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL708784 | 0.79 | SIGMAR1 (0.40) | IDO1SIGMAR1CA1CA2CA9 | |
| SCHEMBL704446 | 0.75 | IDO1 (0.47) | IDO1SIGMAR1 | |
| SCHEMBL705288 | 0.75 | CA1 (0.41) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL3246183 | 0.75 | MAOA (0.59) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL704523 | 0.74 | CA1 (0.44) | HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2 | |
| SCHEMBL29162909 | 0.74 | CA1 (0.48) | MAOAHTR2ACYP2A6SMN1; SMN2TAAR1 | |
| SCHEMBL706090 | 0.74 | KCNH2 (0.45) | MAOAIDO1SIGMAR1 | |
| SCHEMBL19470885 | 0.74 | SIGMAR1 (0.46) | IDO1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274699-B1 | A PROCESS FOR PREPARING ACRYLATE-FUNCTIONAL ORGANOPOLYSILOXANE-URETHANE COPOLYMERS | WACKER-CHEMIE GMBH (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-4762887-A | Process for preparing acrylate-functional organopolysiloxane-urethane copolymers | WACKER SILICONES CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
| EP-0274699-A2 | A process for preparing acrylate-functional organopolysiloxane-urethane copolymers | WACKER-CHEMIE GMBH (DE) | 1988-07-20 | — | — | EP | disclosed |
| US-4606933-A | Acrylate-functional organopolysiloxanes | SWS SILICONES CORPORATION (US) | 1986-08-19 | — | — | US | disclosed |