Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27495940 | 0.84 | TSHR (0.38) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL6467115 | 0.82 | CYP1A2 (0.34) | LMNAF2TSHRALDH1A1HSD17B10 | |
| SCHEMBL20510174 | 0.80 | ALDH1A1 (0.45) | LMNATSHRALDH1A1KDM4EALOX15 | |
| SCHEMBL1897333 | 0.80 | CYP3A4 (0.40) | LMNATSHRALDH1A1HSD17B10CFTR | |
| SCHEMBL106081 | 0.78 | ALDH1A1 (0.56) | TSHRALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL8861756 | 0.78 | MAPK1 (0.42) | LMNAALDH1A1KDM4EPOLBL3MBTL1 | |
| SCHEMBL9411945 | 0.77 | ALDH1A1 (0.48) | LMNATSHRALDH1A1KDM4EPOLB | |
| SCHEMBL7738392 | 0.77 | ALDH1A1 (0.50) | LMNATSHRALDH1A1HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL9411948 | 0.77 | ALDH1A1 (0.54) | TSHRALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL9716853 | 0.75 | ACHE (0.38) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239961-B1 | A SILICONE RUBBER COMPOSITION | Shin-Etsu Chemical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4755554-A | Silicone rubber composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-05 | — | — | US | claimed |
| EP-0239961-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-10-07 | — | — | EP | claimed |
| JP-62232458-A | — | — | None | — | — | JP | disclosed |
| EP-0239961-B1 | A SILICONE RUBBER COMPOSITION | Shin-Etsu Chemical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | disclosed |
| US-4755554-A | Silicone rubber composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-05 | — | — | US | disclosed |
| JP-S62232458-A | SILICONE COMPOSITION | SHIN ETSU CHEM CO LTD | 1987-10-12 | — | — | JP | disclosed |
| EP-0239961-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-10-07 | — | — | EP | disclosed |