Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716901 | 0.81 | ACHE (0.38) | ACHECA12CA1CA2CA7 | |
| SCHEMBL9716977 | 0.79 | ACHE (0.39) | ACHEHPGD | |
| SCHEMBL10627018 | 0.79 | ALDH1A1 (0.41) | HPGD | |
| SCHEMBL9716919 | 0.75 | LMNA (0.41) | CA1CA2CA9 | |
| SCHEMBL9279020 | 0.70 | LMNA (0.50) | ACHECA12CA1CA2CA7 | |
| SCHEMBL3844305 | 0.67 | NPC1 (0.49) | CA12CA2CA9HPGD | |
| SCHEMBL13318430 | 0.67 | ESR1 (0.36) | ACHE | |
| SCHEMBL27502043 | 0.67 | ACHE (0.41) | ACHEHPGD | |
| SCHEMBL6467115 | 0.67 | CYP1A2 (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9730784 | 0.65 | RXRB (0.47) | ACHEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239961-B1 | A SILICONE RUBBER COMPOSITION | Shin-Etsu Chemical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4755554-A | Silicone rubber composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-05 | — | — | US | claimed |
| EP-0239961-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-10-07 | — | — | EP | claimed |
| JP-62232458-A | — | — | None | — | — | JP | disclosed |
| EP-0239961-B1 | A SILICONE RUBBER COMPOSITION | Shin-Etsu Chemical Co., Ltd. (JP) | 1992-10-21 | — | — | EP | disclosed |
| US-4755554-A | Silicone rubber composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-05 | — | — | US | disclosed |
| JP-S62232458-A | SILICONE COMPOSITION | SHIN ETSU CHEM CO LTD | 1987-10-12 | — | — | JP | disclosed |
| EP-0239961-A2 | A silicone rubber composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-10-07 | — | — | EP | disclosed |