Sugi Predict

Sugi Predict / Compounds / SCHEMBL971806

SCHEMBL971806

SCHEMBL971806

OB(c1ccc(Cl)c(Cl)c1)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 1/20 0.46
▸ TTR P02766 1/20 0.45
▸ ORAI1 Q96D31 5/20 0.44
▸ ORAI2 Q96SN7 5/20 0.44
▸ ORAI3 Q9BRQ5 5/20 0.44
▸ TRPV6 Q9H1D0 5/20 0.44
▸ AHR P35869 2/20 0.43
▸ TP53 P04637 1/20 0.43
▸ TSHR P16473 3/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ ENPP2 Q13822 1/20 0.40
▸ PCSK9 Q8NBP7 1/20 0.38
▸ CYP1B1 Q16678 1/20 0.37
▸ HTR3E A5X5Y0 1/20 0.37
▸ HTR3B O95264 1/20 0.37
▸ HTR3A P46098 1/20 0.37
▸ HTR3D Q70Z44 1/20 0.37
▸ HTR3C Q8WXA8 1/20 0.37
▸ EPHX1 P07099 1/20 0.37
▸ EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130450 0.84 TTR (0.61) HSD17B10TTRAHRTP53TSHR
SCHEMBL19712596 0.83 HSD17B10 (0.41) HSD17B10TTRORAI1ORAI2ORAI3
SCHEMBL12050460 0.80 HSD17B10 (0.42) HSD17B10TTRAHRTP53TSHR
SCHEMBL2407029 0.78 TRPV6 (0.46) TTRORAI1ORAI2ORAI3TRPV6
SCHEMBL1138689 0.78 CYP3A4 (0.46) TTRORAI1ORAI2ORAI3TRPV6
SCHEMBL2407140 0.78 ORAI1 (0.46) TTRORAI1ORAI2ORAI3TRPV6
SCHEMBL7085519 0.75 TTR (0.52) HSD17B10TTRAHRTP53ENPP2
SCHEMBL26263783 0.75 TTR (0.38) HSD17B10TTRAHRTP53TSHR
SCHEMBL3016981 0.75 TTR (0.38) HSD17B10TTRAHRTP53TSHR
SCHEMBL21913496 0.74 AHR (0.43) HSD17B10TTRAHRTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3024836-B1 IMPROVED METHOD FOR THE PREPARATION OF CHLORINATED BIPHENYLANILIDES AND BIPHENYLANILINES BAYER CROPSCIENCE AG (DE) 2018-07-11 — — EP claimed
US-20180093942-A1 PROCESS FOR PREPARING CHLORINATED BIPHENYLANILIDES AND BIPHENYLANILINES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-04-05 — — US claimed
US-9868694-B2 Process for preparing chlorinated biphenylanilides and biphenylanilines BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-16 — — US claimed
EP-2280932-B1 Process for preparing substituted biphenylanilides BAYER IP GMBH (DE) 2017-10-18 — — EP claimed
US-20160280635-A1 IMPROVED PROCESS FOR PREPARING CHLORINATED BIPHENYLANILIDES AND BIPHENYLANILINES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-09-29 — — US claimed
EP-3024836-A1 IMPROVED PROCESS FOR PREPARING CHLORINATED BIPHENYLANILIDES AND BIPHENYLANILINES Bayer CropScience Aktiengesellschaft (DE) 2016-06-01 — — EP claimed
EP-2185500-B1 METHOD FOR MANUFACTURING BIARYLS BAYER IP GMBH (DE) 2015-12-23 — — EP claimed
WO-2015011032-A1 IMPROVED PROCESS FOR PREPARING CHLORINATED BIPHENYLANILIDES AND BIPHENYLANILINES BAYER CROPSCIENCE AG (DE) 2015-01-29 — — WO claimed
US-8455689-B2 Process for preparing substituted biphenylanilides BAYER CROPSCIENCE AG (DE) 2013-06-04 — — US claimed
EP-2257530-B1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES BAYER CROPSCIENCE AG (DE) 2011-10-12 — — EP claimed
EP-2280932-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES Bayer CropScience AG (DE) 2011-02-09 — — EP claimed
US-20110003999-A1 Process for Preparing Substituted Biphenylanilides BAYER CROPSCIENCE AG (DE) 2011-01-06 — — US claimed
US-20100185015-A1 Process for preparing biaryls BAYER CROPSCIENCE AG (DE) 2010-07-22 — — US claimed
US-7709684-B2 Process for preparing substituted biphenyls BASF SE (DE) 2010-05-04 — — US claimed
EP-2119697-A1 Process for preparing substituted biphenylanilides Bayer CropScience AG (DE) 2009-11-18 — — EP claimed
WO-2009135598-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES BAYER CROPSCIENCE AG 2009-11-12 — — WO claimed
EP-2093216-A1 Process for preparing substituted biphenylanilides Bayer CropScience AG (DE) 2009-08-26 — — EP claimed
EP-2029519-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BASF SE (DE) 2009-03-04 — — EP claimed
US-20090005597-A1 Process for Preparing Substituted Biphenyls BASF SE (DE) 2009-01-01 — — US claimed
WO-2007138089-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BASF SE (DE) 2007-12-06 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005597-A1 Process for Preparing Substituted Biphenyls CBR3, HRH3, CBR1 HSD17B10 563/4885TTR 1469/4885ORAI1 4540/4885
US-20180093942-A1 PROCESS FOR PREPARING CHLORINATED BIPHENYLANILIDES AND BIPHENYLANILINES DDT, CBR3, MSRB3 HSD17B10 2317/4885TTR 1978/4885ORAI1 3694/4885
US-20160280635-A1 IMPROVED PROCESS FOR PREPARING CHLORINATED BIPHENYLANILIDES AND BIPHENYLANILINES CYP2F1, CYP1A1, CYP4F12 HSD17B10 1289/4885TTR 652/4885ORAI1 4823/4885
US-20100185015-A1 Process for preparing biaryls AGPS, PAPSS1, BRPF1 HSD17B10 3401/4885TTR 3434/4885ORAI1 4650/4885
US-20110003999-A1 Process for Preparing Substituted Biphenylanilides DDT, PAH, THOP1 HSD17B10 371/4885TTR 680/4885ORAI1 4607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.