Shogaol

Shogaol

SCHEMBL971812

CCCCC/C=C/C(=O)CCc1ccc(O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 1.00
CYP1A2 P05177 5/20 1.00
CYP3A4 P08684 5/20 1.00
TRPV1 Q8NER1 5/20 1.00
HTR1A P08908 4/20 1.00
CYP2C8 P10632 4/20 1.00
CYP2C9 P11712 4/20 1.00
CYP2B6 P20813 4/20 1.00
CYP2C19 P33261 4/20 1.00
CYP2D6 P10635 3/20 1.00
CYP2E1 P05181 2/20 1.00
CYP2A6 P11509 2/20 1.00
ALOX5 P09917 1/20 1.00
MAPT P10636 2/20 0.62
HPGD P15428 2/20 0.62
MEN1 O00255 1/20 0.62
TP53 P04637 1/20 0.62
MTOR P42345 1/20 0.62
KMT2A Q03164 1/20 0.62
ALDH1A1 P00352 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Shogaol SCHEMBL10523393 1.00 LTA4H (1.00) LTA4HCYP1A2CYP3A4TRPV1HTR1A
Shogaol SCHEMBL29423038 1.00 LTA4H (1.00) LTA4HCYP1A2CYP3A4TRPV1HTR1A
Shogaol SCHEMBL29711754 1.00 LTA4H (1.00) LTA4HCYP1A2CYP3A4TRPV1HTR1A
Shogaol SCHEMBL29475328 1.00 LTA4H (1.00) LTA4HCYP1A2CYP3A4TRPV1HTR1A
Shogaol SCHEMBL49054 1.00 LTA4H (1.00) LTA4HCYP1A2CYP3A4TRPV1HTR1A
SCHEMBL4885150 0.99 HTR1A (1.00) LTA4HCYP1A2CYP3A4TRPV1HTR1A
SCHEMBL4886648 0.99 HTR1A (1.00) LTA4HCYP1A2CYP3A4TRPV1HTR1A
SCHEMBL4886657 0.99 HTR1A (1.00) LTA4HCYP1A2CYP3A4TRPV1HTR1A
SCHEMBL4885163 0.99 HTR1A (1.00) LTA4HCYP1A2CYP3A4TRPV1HTR1A
SCHEMBL29929375 0.99 HTR1A (1.00) LTA4HCYP1A2CYP3A4TRPV1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 757 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144780-A1 COMPOSITION FOR ENHANCING ADRENOMEDULLIN GENE EXPRESSION HOUSE WELLNESS FOODS CORPORATION (JP) 2026-05-28 US claimed
WO-2026043428-A1 METHOD OF PREPARING GINGER EXTRACT, COMPOSITION COMPRISING SAID GINGER EXTRACT AND USE THEREOF CHULABHORN FOUNDATION (TH) 2026-02-26 WO claimed
US-12478091-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-11-25 US claimed
WO-2025202300-A1 COMPLEX COACERVATES FOR NUTRACEUTICALS NEKTIUM PHARMA S.L. (ES) 2025-10-02 WO claimed
EP-4623703-A1 COMPLEX COACERVATES FOR NUTRACEUTICALS Nektium Pharma S.L. (ES) 2025-10-01 EP claimed
US-20250295668-A1 METHODS FOR INDUCING COLANIC ACID BIOSYNTHESIS HOWARD HUGHES MEDICAL INSTITUTE (US) 2025-09-25 US claimed
EP-4615506-A1 USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES Sahin, Fikret (TR) 2025-09-17 EP claimed
EP-4599698-A1 PRODUCTS COMPRISING SENSORY AGENTS Nicoventures Trading Limited (GB) 2025-08-13 EP claimed
EP-4593977-A1 PRODUCTS AND METHODS RELATED TO THE DISTILLATION OF MOLECULES FROM AEROSOLS Natural Extraction Systems, LLC (US) 2025-08-06 EP claimed
EP-4588470-A1 PHARMACEUTICAL COMPOSITION COMPRISING CURCUMIN AND THE PREPARATION THEREOF Löffler, Bernd-Michael (DE) 2025-07-23 EP claimed
CN-106659789-A Cyp2j2 antagonists in the treatment of pain 弗劳恩霍夫应用研究促进协会 2017-05-10 CN claimed
CN-106645450-A Quality detection method for novel biological particle 南京中医药大学 2017-05-10 CN claimed
CN-106474383-A A kind of pharmaceutical composition treating acute bronchitiss 河南水晶头文化传媒有限公司 2017-03-08 CN claimed
CN-105491894-A Agent for imparting alcoholic feeling HASEGAWA T CO LTD 2016-04-13 CN claimed
CN-105007947-A Solid solution compositions and their use in cardiovascular disease BIOCOPEA LTD 2015-10-28 CN claimed
CN-104981253-A Solid solution compositions and use in chronic inflammation BIOCOPEA LTD 2015-10-14 CN claimed
CN-104968368-A Solid solution compositions and their use in severe pain INFIRST HEALTHCARE LTD 2015-10-07 CN claimed
CN-103391768-A Compostions and methods for treating chronic inflammation and inflammatory diseases BIOCOPEA LTD 2013-11-13 CN claimed
CN-103391767-A Compositions and methods for treating cardiovascular disease BIOCOPEA LTD 2013-11-13 CN claimed
CN-102266547-B Preparation method of ginger extract with detoxifying effect on exogenous carcinogens and product UNIV NANJING FINANCE & ECO 2013-06-12 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144780-A1 COMPOSITION FOR ENHANCING ADRENOMEDULLIN GENE EXPRESSION TRPA1, TRPV1, TRPM6 LTA4H 1137/4885CYP1A2 2094/4885CYP3A4 2359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.