SCHEMBL4886648

SCHEMBL4886648

CCCCCCC/C=C/C(=O)CCc1ccc(O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 5/20 1.00
LTA4H P09960 5/20 0.98
CYP3A4 P08684 5/20 0.98
CYP1A2 P05177 4/20 0.98
TRPV1 Q8NER1 4/20 0.98
CYP2C8 P10632 4/20 0.98
CYP2C9 P11712 4/20 0.98
CYP2B6 P20813 4/20 0.98
CYP2C19 P33261 4/20 0.98
CYP2D6 P10635 4/20 0.98
CYP2A6 P11509 3/20 0.98
CYP2E1 P05181 2/20 0.98
ALOX5 P09917 1/20 0.98
MAPT P10636 2/20 0.64
HPGD P15428 2/20 0.64
MEN1 O00255 1/20 0.64
TP53 P04637 1/20 0.64
MTOR P42345 1/20 0.64
KMT2A Q03164 1/20 0.64
ALDH1A1 P00352 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29564343 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL4886657 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL30335074 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL29564502 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL29929375 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL4885163 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL4885150 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
Shogaol SCHEMBL971812 0.99 LTA4H (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
Shogaol SCHEMBL10523393 0.99 LTA4H (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
Shogaol SCHEMBL49054 0.99 LTA4H (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026043428-A1 METHOD OF PREPARING GINGER EXTRACT, COMPOSITION COMPRISING SAID GINGER EXTRACT AND USE THEREOF CHULABHORN FOUNDATION (TH) 2026-02-26 WO claimed
EP-4588470-A1 PHARMACEUTICAL COMPOSITION COMPRISING CURCUMIN AND THE PREPARATION THEREOF Löffler, Bernd-Michael (DE) 2025-07-23 EP claimed
CN-120131997-A Auxiliary agent for slow-releasing anticancer medicine and its preparation method 苏州康纯医药科技有限公司 2025-06-13 CN claimed
CN-115586283-B Characteristic metabolite-based dried ginger origin tracing method 南京中医药大学 2025-05-02 CN claimed
CN-119280430-B Anticancer drug auxiliary agent with slow release function and preparation method thereof 苏州康纯医药科技有限公司 2025-03-28 CN claimed
CN-119280430-A Anticancer drug auxiliary agent with slow release function and preparation method thereof 苏州康纯医药科技有限公司 2025-01-10 CN claimed
US-20240226224-A1 COMPOSITIONS GIVAUDAN SA (CH) 2024-07-11 US claimed
EP-4395744-A1 GELLED COMPOSITION BASED ON GINGER EXTRACT PETIT MEDICAL GROUP S.R.L.S. (IT) 2024-07-10 EP claimed
US-20240207350-A1 COMBINATION PREPARATION CONTAINING RESVERATROL LOEFFLER, BERND-MICHAEL (DE) 2024-06-27 US claimed
EP-4329788-A1 COMPOSITIONS Givaudan SA (CH) 2024-03-06 EP claimed
CN-117562882-A Composition for selectively inhibiting activity of uridine diphosphate glucuronyltransferase 1A9 and application thereof 大连医科大学 2024-02-20 CN claimed
CN-114216979-B Dried ginger quality evaluation method based on UPLC-TQ-MS/MS 暨南大学 2023-08-01 CN claimed
WO-2023031699-A1 GELLED COMPOSITION BASED ON GINGER EXTRACT BIOSOLVING S.R.L. (IT) 2023-03-09 WO claimed
CN-115586283-A Dried ginger producing area tracing method based on characteristic metabolites 南京中医药大学 2023-01-10 CN claimed
CN-115469044-A Liquid chromatography-tandem mass spectrometry detection method for gingerol in ginger rhizome, overground stem and leaf 中国农业科学院农业质量标准与检测技术研究所 2022-12-13 CN claimed
WO-2022229320-A1 COMPOSITIONS GIVAUDAN SA (CH) 2022-11-03 WO claimed
CN-113030329-B One-test-multiple-evaluation method for determining content of 6 gingerol components in ginger juice brown sugar 广东省科学院生物工程研究所 2022-10-11 CN claimed
CN-114216979-A Dry ginger quality evaluation method based on UPLC-TQ-MS/MS 暨南大学 2022-03-22 CN claimed
US-20260144264-A1 ZINGIBERACEAE PLANT EXTRACT AND COMPOSITION THEREOF AND USE IN PEST CONTROL CHENGDU NEWSUN CROP SCIENCE CO., LTD. (CN) 2026-05-28 US disclosed
US-20070003641-A1 Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease KIM DARRICK S H 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070003641-A1 Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease APP, BACE1, GSAP HTR1A 2494/4885LTA4H 1783/4885CYP3A4 3043/4885
US-20260144264-A1 ZINGIBERACEAE PLANT EXTRACT AND COMPOSITION THEREOF AND USE IN PEST CONTROL DDT, CARM1, LAGE3 HTR1A 4689/4885LTA4H 879/4885CYP3A4 236/4885
US-20240207350-A1 COMBINATION PREPARATION CONTAINING RESVERATROL VDR, NR1H3, NR1H2 HTR1A 1162/4885LTA4H 2256/4885CYP3A4 339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.