SCHEMBL4885163

SCHEMBL4885163

CCCCCCCCCC=CC(=O)CCc1ccc(O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 5/20 1.00
LTA4H P09960 5/20 0.98
CYP3A4 P08684 5/20 0.98
CYP1A2 P05177 4/20 0.98
TRPV1 Q8NER1 4/20 0.98
CYP2C8 P10632 4/20 0.98
CYP2C9 P11712 4/20 0.98
CYP2B6 P20813 4/20 0.98
CYP2C19 P33261 4/20 0.98
CYP2D6 P10635 4/20 0.98
CYP2A6 P11509 3/20 0.98
CYP2E1 P05181 2/20 0.98
ALOX5 P09917 1/20 0.98
MAPT P10636 2/20 0.64
HPGD P15428 2/20 0.64
MEN1 O00255 1/20 0.64
TP53 P04637 1/20 0.64
MTOR P42345 1/20 0.64
KMT2A Q03164 1/20 0.64
ALDH1A1 P00352 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4886648 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL29564343 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL4886657 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL30335074 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL29564502 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL29929375 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
SCHEMBL4885150 1.00 HTR1A (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
Shogaol SCHEMBL971812 0.99 LTA4H (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
Shogaol SCHEMBL10523393 0.99 LTA4H (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1
Shogaol SCHEMBL49054 0.99 LTA4H (1.00) HTR1ALTA4HCYP3A4CYP1A2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO claimed
US-12588699-B2 Aerosol-generating substrate PHILIP MORRIS PRODUCTS S.A. (CH) 2026-03-31 US disclosed
US-12342845-B2 Aerosol-generating substrate comprising Zingiber species PHILIP MORRIS PRODUCTS S.A. (CH) 2025-07-01 US disclosed
EP-4048095-B1 NOVEL AEROSOL-GENERATING SUBSTRATE COMPRISING ZINGIBER SPECIES PHILIP MORRIS PRODUCTS SA (CH) 2023-11-29 EP disclosed
US-20230346001-A1 NOVEL AEROSOL-GENERATING SUBSTRATE PHILIP MORRIS PRODUCTS S.A. (CH) 2023-11-02 US disclosed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 WO disclosed
CN-115666278-A Novel aerosol-generating substrate 菲利普莫里斯生产公司 2023-01-31 CN disclosed
EP-4110093-A1 NOVEL AEROSOL-GENERATING SUBSTRATE Philip Morris Products S.A. (CH) 2023-01-04 EP disclosed
US-11540539-B2 Reduced sodium food products GENERAL MILLS, INC. (US) 2023-01-03 US disclosed
US-20220369690-A1 NOVEL AEROSOL-GENERATING SUBSTRATE COMPRISING ZINGIBER SPECIES PHILIP MORRIS PRODUCTS S.A. (CH) 2022-11-24 US disclosed
US-20150283193-A9 Compositions for Alleviating Inflammation and Oxidative Stress in a Mammal LIFELINE NUTRACEUTICALS (US) 2015-10-08 US disclosed
US-20140271944-A1 Compositions for Alleviating Inflammation and Oxidative Stress in a Mammal LIFELINE NUTRACEUTICALS (US) 2014-09-18 US disclosed
US-20140271944-A1 Compositions for Alleviating Inflammation and Oxidative Stress in a Mammal LIFELINE NUTRACEUTICALS (US) 2014-09-18 US disclosed
US-7728043-B2 Methods for treatment of beta-amyloid protein-induced ocular disease KIM DARRICK S H L 2010-06-01 US disclosed
US-7572829-B2 Pharmaceutical compositions useful in prevention and treatment of Beta-amyloid protein-induced disease KIM DARRICK S H L 2009-08-11 US disclosed
US-20090011059-A1 Ginger Extract For Inhibiting Human Drug Transporters BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-01-08 US disclosed
US-20080085932-A1 Pharmaceutical Compositions Useful In Prevention and Treatment of Beta-Amyloid Protein-Induced Disease KIM DARRICK S 2008-04-10 US disclosed
US-20080038386-A1 Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition MOZA ASHOK K 2008-02-14 US disclosed
WO-2007071721-A2 GINGER EXTRACT FOR INHIBITING HUMAN DRUG TRANSPORTERS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-06-28 WO disclosed
US-20070003641-A1 Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease KIM DARRICK S H 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070003641-A1 Synergistic pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease APP, BACE1, GSAP HTR1A 2494/4885LTA4H 1783/4885CYP3A4 3043/4885
US-20090011059-A1 Ginger Extract For Inhibiting Human Drug Transporters ABCB1, SLCO1B1, ABCG2 HTR1A 1373/4885LTA4H 2604/4885CYP3A4 151/4885
US-20140271944-A1 Compositions for Alleviating Inflammation and Oxidative Stress in a Mammal GSTO1, GSTK1, GSTP1 HTR1A 4032/4885LTA4H 504/4885CYP3A4 1302/4885
US-20080085932-A1 Pharmaceutical Compositions Useful In Prevention and Treatment of Beta-Amyloid Protein-Induced Disease APP, BACE1, PSEN1 HTR1A 2714/4885LTA4H 971/4885CYP3A4 733/4885
US-20150283193-A9 Compositions for Alleviating Inflammation and Oxidative Stress in a Mammal GSTO1, GSTK1, GSTP1 HTR1A 4032/4885LTA4H 504/4885CYP3A4 1302/4885
US-12588699-B2 Aerosol-generating substrate CCT5, PRUNE1, DSTN HTR1A 2279/4885LTA4H 3290/4885CYP3A4 1241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.