Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718380 | 0.88 | TBXAS1 (0.63) | TBXAS1TBXA2R | |
| SCHEMBL9718385 | 0.82 | ALDH1A1 (0.64) | TBXAS1TBXA2R | |
| SCHEMBL9718429 | 0.81 | TBXA2R (0.59) | TBXAS1TBXA2R | |
| SCHEMBL9718387 | 0.81 | ALDH1A1 (0.62) | TBXAS1TBXA2R | |
| SCHEMBL1403453 | 0.78 | ALDH1A1 (0.54) | TBXAS1TBXA2R | |
| SCHEMBL9718405 | 0.78 | PKM (0.57) | — | |
| SCHEMBL9659259 | 0.75 | ALDH1A1 (0.71) | TBXAS1TBXA2R | |
| SCHEMBL6863607 | 0.74 | ALDH1A1 (0.60) | TBXAS1 | |
| SCHEMBL30109394 | 0.74 | ALDH1A1 (0.60) | TBXAS1 | |
| SCHEMBL10463166 | 0.73 | ALDH1A1 (0.61) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260527-B1 | SYNERGETIC COMBINATION COMPRISING A PHOSPHODIESTERASE INHIBITOR AND A THROMBOXAN-A2-ANTAGONIST, AND THEIR USE OR MANUFACTURE | Dr. Karl Thomae GmbH (DE) | 1992-04-01 | — | — | EP | disclosed |
| EP-0194548-A2 | Sulfonylaminoethyl compounds, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1986-09-17 | — | — | EP | disclosed |