Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718845 | 0.73 | RAB9A (0.60) | ALDH1A1GAARAB9ANPC1PKM | |
| SCHEMBL3498646 | 0.73 | NPC1 (0.54) | ALDH1A1GAARAB9ANPC1PKM | |
| SCHEMBL970884 | 0.67 | NPC1 (0.31) | ALDH1A1RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL24155568 | 0.65 | NPC1 (0.57) | ALDH1A1GAARAB9ANPC1PKM | |
| SCHEMBL834683 | 0.63 | MAPT (0.50) | ALDH1A1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16004922 | 0.62 | MEN1 (0.46) | ALDH1A1GAARAB9ANPC1PKM | |
| SCHEMBL6420569 | 0.61 | PRKCD (0.55) | RAB9ANPC1ATMMAPT | |
| SCHEMBL6644807 | 0.60 | ALDH1A1 (0.50) | ALDH1A1GAARAB9ANPC1PKM | |
| Bromide SCHEMBL3354419 | 0.60 | KMT2A (0.58) | ALDH1A1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28418261 | 0.60 | MAPT (0.50) | ALDH1A1GAARAB9ANPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120839-A1 | PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120839-A1 | PYRAZOLES USEFUL IN THE TREATMENT OF INFLAMMATION | ALOX15, ALOX12, ALOX15B | PSEN1 2607/4885PSEN2 2552/4885APH1B 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.