SCHEMBL9833894

SCHEMBL9833894

Nc1c(O)ccc(Cl)c1C(=O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.45
ALDH1A1 P00352 3/20 0.45
MAPK14 Q16539 1/20 0.43
MAPT P10636 2/20 0.43
GAA P10253 2/20 0.43
CNR1 P21554 1/20 0.42
ALOX15 P16050 1/20 0.42
PBRM1 Q86U86 1/20 0.42
DPP4 P27487 1/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
ATM Q13315 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
VCAM1 P19320 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9719338 0.81 MAPT (0.50) ALDH1A1MAPK14MAPTGAAPBRM1
SCHEMBL11210134 0.81 MEN1 (0.50) CNR2ALDH1A1MAPTGAACNR1
SCHEMBL5056827 0.81 AKR1C3 (0.48) ALDH1A1MAPK14MAPTGAAALOX15
SCHEMBL27746569 0.80 DPP4 (0.52) CNR2ALDH1A1CNR1DPP4LMNA
SCHEMBL28147122 0.79 CASP7 (0.52) ALDH1A1MAPTGAAALOX15PBRM1
SCHEMBL206143 0.77 DPP4 (0.42) ALDH1A1MAPTALOX15PBRM1DPP4
SCHEMBL9747962 0.77 ABCB11 (0.47) LMNAKMT2AHPGD
SCHEMBL533764 0.76 ALDH1A1 (0.50) CNR2ALDH1A1MAPTGAACNR1
SCHEMBL6129712 0.76 THRB (0.43) ALDH1A1MAPTGAAALOX15DPP4
SCHEMBL9358127 0.75 ALDH1A1 (0.54) ALDH1A1MAPTGAAPBRM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0217149-B1 POLY(2,2,6,6-TETRAMETHYLPIPERIDYLAMINOSPIROGLYCOLETHER-1,3,5-TRIAZINES) ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-01-30 EP disclosed
EP-0095031-A2 N,N,N-tris(2,2,6,6,-tetramethyl-4-piperidone ketal)-1,3,5-triazines and synthetic resin compositions ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1983-11-30 EP disclosed