Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111113 | 0.80 | CYP19A1 (0.47) | MAPTNPC1RAB9ACYP19A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9719344 | 0.79 | CYP19A1 (0.46) | MAPTNPC1RAB9ACYP19A1SMN1; SMN2 | |
| SCHEMBL9269160 | 0.73 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL9266327 | 0.73 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL17500281 | 0.71 | RXRA (0.49) | MAPTALDH1A1PKM | |
| SCHEMBL10965346 | 0.71 | HTR7 (0.62) | S100A4MAPTNPC1RAB9AHTR7 | |
| SCHEMBL9267697 | 0.70 | KCNQ2 (0.57) | S100A4MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL7983280 | 0.69 | CYP19A1 (0.39) | MAPTALDH1A1KDM4ERECQLMEN1 | |
| Hydrochloric Acid SCHEMBL9266879 | 0.69 | KCNQ2 (0.56) | S100A4MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL17022656 | 0.68 | HTR2A (0.56) | MAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000760-A1 | METHOD OF TREATING NEUROLOGICAL DYSFUNCTION USING NEUROTRANSMITTER ENHANCES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-01-23 | — | — | WO | disclosed |