Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311711 | 0.89 | KMT2A (0.44) | MAPK1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28975450 | 0.88 | MAPK1 (0.48) | MAPK1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9719908 | 0.84 | L3MBTL1 (0.46) | MAPK1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9719895 | 0.80 | ALDH1A1 (0.38) | MAPK1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL14032275 | 0.77 | MAPK1 (0.46) | MAPK1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL24983762 | 0.77 | L3MBTL1 (0.50) | MAPK1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL12499466 | 0.77 | AKR1C3 (0.54) | MAPK1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL500044 | 0.77 | AKR1C3 (0.54) | MAPK1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7166547 | 0.77 | AKR1C3 (0.54) | MAPK1KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL10411176 | 0.76 | L3MBTL1 (0.49) | MAPK1KMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132463-A | Cardiovascular, skin, kidney, respiratory system, and gastrointestinal disorders | MERCK & CO., INC. (US) | 1992-07-21 | — | — | US | disclosed |
| US-5047420-A | Platelet activating factor | MERCK & CO., INC. (US) | 1991-09-10 | — | — | US | disclosed |