Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719960 | 0.90 | L3MBTL1 (0.38) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9719904 | 0.80 | MAPK1 (0.49) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9719899 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL7311711 | 0.72 | KMT2A (0.44) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL28975450 | 0.71 | MAPK1 (0.48) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9719067 | 0.70 | SMN1; SMN2 (0.39) | ALDH1A1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL9719922 | 0.68 | POLB (0.39) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9719908 | 0.68 | L3MBTL1 (0.46) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL9719906 | 0.67 | BPTF (0.35) | ALDH1A1KDM4EMAPK1BPTFPOLB | |
| SCHEMBL9719903 | 0.67 | BPTF (0.35) | ALDH1A1KDM4EMAPK1BPTFPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132463-A | Cardiovascular, skin, kidney, respiratory system, and gastrointestinal disorders | MERCK & CO., INC. (US) | 1992-07-21 | — | — | US | disclosed |
| US-5047420-A | Platelet activating factor | MERCK & CO., INC. (US) | 1991-09-10 | — | — | US | disclosed |