Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719895 | 0.90 | ALDH1A1 (0.38) | L3MBTL1MAPK1BPTFKDM4EALDH1A1 | |
| SCHEMBL9719067 | 0.81 | SMN1; SMN2 (0.39) | L3MBTL1MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9719908 | 0.80 | L3MBTL1 (0.46) | L3MBTL1MAPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL9719963 | 0.75 | L3MBTL1 (0.36) | L3MBTL1MAPK1BPTFKDM4EALDH1A1 | |
| SCHEMBL7166547 | 0.74 | AKR1C3 (0.54) | L3MBTL1MAPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL12499466 | 0.74 | AKR1C3 (0.54) | L3MBTL1MAPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL500044 | 0.74 | AKR1C3 (0.54) | L3MBTL1MAPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL7317653 | 0.72 | POLB (0.45) | L3MBTL1MAPK1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9719058 | 0.72 | ALDH1A1 (0.43) | L3MBTL1MAPK1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9719894 | 0.70 | PTAFR (0.37) | KDM4EALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132463-A | Cardiovascular, skin, kidney, respiratory system, and gastrointestinal disorders | MERCK & CO., INC. (US) | 1992-07-21 | — | — | US | disclosed |
| US-5047420-A | Platelet activating factor | MERCK & CO., INC. (US) | 1991-09-10 | — | — | US | disclosed |