Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL3456475 | 0.82 | ACHE (0.58) | LMNATSHRALOX12ACHEPKM | |
| SCHEMBL215145 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL10834718 | 0.78 | — | — | |
| Toluene SCHEMBL3455474 | 0.76 | LMNA (0.44) | LMNATSHRALOX12ACHEPKM | |
| Phenylacetaldehyde SCHEMBL217860 | 0.76 | TAAR1 (0.43) | TSHRTAAR1KMT2AMEN1 | |
| P-Xylene SCHEMBL406649 | 0.73 | KMT2A (0.42) | LMNAACHEPKMKIF11KMT2A | |
| Toluene SCHEMBL4171207 | 0.71 | ACHE (0.61) | LMNATSHRALOX12ACHEPKM | |
| Benzaldehyde SCHEMBL432383 | 0.71 | ALDH1A1 (0.61) | LMNATSHRKMT2AALDH1A1 | |
| Toluene SCHEMBL9720131 | 0.71 | LMNA (0.48) | LMNATSHRALOX12ACHETAAR1 | |
| Toluene SCHEMBL27263598 | 0.71 | LMNA (0.48) | LMNATSHRALOX12ACHETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153196-A | Administering for reduction of neurotransmission in nervous system disorders | ELI LILLY AND COMPANY (US) | 1992-10-06 | — | — | US | disclosed |