Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL3455474 | 0.87 | LMNA (0.44) | ACHELMNATSHRALOX12KEAP1 | |
| P-Xylene SCHEMBL828120 | 0.86 | ACHE (0.50) | ACHELMNATSHRALOX12TDP1 | |
| Toluene SCHEMBL9720129 | 0.82 | LMNA (0.39) | ACHELMNATSHRALOX12KEAP1 | |
| Toluene SCHEMBL4171207 | 0.81 | ACHE (0.61) | ACHELMNATSHRALOX12CA4 | |
| Toluene SCHEMBL9799867 | 0.80 | ACHE (0.79) | ACHELMNATSHRALOX12CA4 | |
| Benzene SCHEMBL3361615 | 0.80 | THRB (0.30) | CA4THRB | |
| Toluene SCHEMBL8572276 | 0.79 | LMNA (0.58) | ACHELMNATSHRALOX12CA4 | |
| Toluene SCHEMBL8844853 | 0.77 | ACHE (0.73) | ACHELMNATSHRALOX12HPGD | |
| Toluene SCHEMBL7645369 | 0.76 | — | — | |
| Toluene SCHEMBL8824270 | 0.76 | ACHE (1.00) | ACHELMNATSHRALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119354-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORP (US) | 2022-04-21 | — | — | US | disclosed |
| EP-3917914-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020160202-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2020-08-06 | — | — | WO | disclosed |
| CN-105593206-B | Hole mobile material | 默克专利有限公司 | 2017-10-10 | — | — | CN | disclosed |
| CN-106220482-A | Aromatic compound containing side chain | 味之素株式会社 | 2016-12-14 | — | — | CN | disclosed |
| US-8273744-B2 | AMPK modulators | MERCURY THERAPEUTICS, INC. (US) | 2012-09-25 | — | — | US | disclosed |
| EP-2240016-A1 | AMPK MODULATORS | Mercury Therapeutics, Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| US-20100009992-A1 | AMPK MODULATORS | MERCURY THERAPEUTICS, INC. | 2010-01-14 | — | — | US | disclosed |
| WO-2009100130-A1 | AMPK MODULATORS | MERCURY THERAPEUTICS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
| EP-1255739-B1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-1998052915-A2 | LEUKOTRIENE B4 DERIVATIVES, IN PARTICULAR OXIMO-LTB4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |
| WO-1998052916-A1 | NOVEL LEUKOTRIENE-B DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |
| US-5401762-A | Treatment of high blood pressure, Parkinson*s disease, schizophrenia, dopamine receptors | BASF AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| US-5164388-A | Hypotensive agents, treatment of congestive heart failure | ABBOTT LABORATORIES (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0439556-A4 | HETEROCYCLIC PEPTIDE RENIN INHIBITORS | — | 1991-10-30 | — | — | EP | disclosed |
| EP-0439556-A1 | HETEROCYCLIC PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1991-08-07 | — | — | EP | disclosed |
| WO-1990004917-A1 | HETEROCYCLIC PEPTIDE RENIN INHIBITORS | ABBOTT LABORATORIES (US) | 1990-05-17 | — | — | WO | disclosed |
| EP-0365992-A1 | Heterocyclic peptide renin inhibitors | ABBOTT LABORATORIES (US) | 1990-05-02 | — | — | EP | disclosed |
| US-4847377-A | ANTIHYPERPROLIFERATIVE SKIN DISEASES | SCHERING CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| US-4816458-A | TOPICAL ADMINISTERING | SCHERING CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119354-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | DDX41, AOC1, DPYD | ACHE 413/4885LMNA 4417/4885TSHR 1458/4885 |
| US-20100009992-A1 | AMPK MODULATORS | PRKAG1, PRKAG2, PRKAG3 | ACHE 3859/4885LMNA 4131/4885TSHR 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.