Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 7/20 | 0.34 |
| ▸ | THRA | P10827 | 6/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DNM2 | P50570 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720214 | 0.84 | MEN1 (0.54) | SPHK1PLA2G2ATHRBHTTMEN1 | |
| SCHEMBL10385452 | 0.84 | MEN1 (0.54) | SPHK1PLA2G2ATHRBHTTMEN1 | |
| Hydrochloric Acid SCHEMBL10385000 | 0.82 | PRKD3 (0.55) | PLA2G2AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10385534 | 0.82 | PRKD3 (0.55) | PLA2G2AMEN1KMT2A | |
| SCHEMBL9720263 | 0.80 | PLA2G2A (0.38) | PLA2G2ATHRBHTTMEN1KMT2A | |
| SCHEMBL9720221 | 0.80 | PLA2G2A (0.38) | PLA2G2ATHRBHTTMEN1KMT2A | |
| SCHEMBL9720161 | 0.78 | PLA2G2A (0.41) | PLA2G2A | |
| Hydrochloric Acid SCHEMBL10385523 | 0.77 | ACHE (0.48) | PLA2G2A | |
| SCHEMBL9720198 | 0.77 | PLA2G2A (0.39) | PLA2G2AUSP2 | |
| SCHEMBL9720202 | 0.76 | ALDH1A1 (0.48) | HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |