Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720718 | 0.88 | TRPV6 (0.58) | GAAMAPTKDM4EALDH1A1ATM | |
| SCHEMBL14825427 | 0.80 | ATM (0.58) | ALDH1A1ATMKMT2AMEN1 | |
| SCHEMBL10514806 | 0.80 | ATM (0.58) | GAASMN1; SMN2ATMKMT2AMEN1 | |
| SCHEMBL14825426 | 0.78 | ATM (0.56) | ALDH1A1ATMKMT2AMEN1OPRD1 | |
| SCHEMBL1152689 | 0.77 | LMNA (0.55) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1152693 | 0.77 | LMNA (0.55) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7311276 | 0.77 | ATM (0.84) | GAAKDM4ESMN1; SMN2ATMKMT2A | |
| Belarizine SCHEMBL2108057 | 0.76 | ATM (0.73) | MAPTKDM4EALDH1A1ATMKMT2A | |
| SCHEMBL9720726 | 0.76 | KDM4E (0.79) | GAAMAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL9720716 | 0.76 | OPRD1 (0.70) | GAASMN1; SMN2ATMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |