Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | CCR5 | P51681 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CCR2 | P41597 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766190 | 0.82 | CCR2 (0.84) | SIGMAR1CCR5CCR2 | |
| SCHEMBL9720795 | 0.81 | CCR2 (0.54) | SIGMAR1CCR2 | |
| SCHEMBL6770892 | 0.79 | CCR2 (0.87) | CCR5CCR2 | |
| SCHEMBL11848227 | 0.79 | CCR2 (0.73) | SIGMAR1CCR2KDM4E | |
| SCHEMBL9720800 | 0.79 | SIGMAR1 (0.56) | SIGMAR1MAPK1 | |
| Hydrochloric Acid SCHEMBL11838606 | 0.77 | CCR2 (0.71) | SIGMAR1CCR2KDM4E | |
| SCHEMBL28217942 | 0.77 | SIGMAR1 (1.00) | SIGMAR1KDM4E | |
| SCHEMBL8963508 | 0.77 | HTR1A (0.53) | SIGMAR1CCR5MAPTTDP1HTR1A | |
| SCHEMBL11842606 | 0.77 | CCR5 (0.60) | SIGMAR1CCR5KDM4EMAPK1 | |
| SCHEMBL25326051 | 0.76 | SIGMAR1 (0.64) | SIGMAR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |