Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6766190 | 0.88 | CCR2 (0.84) | CCR2CCR5 | |
| SCHEMBL6770131 | 0.82 | CCR2 (0.78) | CCR2 | |
| SCHEMBL9720774 | 0.79 | SIGMAR1 (0.60) | CCR2CCR5 | |
| SCHEMBL6770148 | 0.79 | CCR2 (0.81) | CCR2 | |
| SCHEMBL9720795 | 0.76 | CCR2 (0.54) | CCR2 | |
| SCHEMBL6765872 | 0.76 | CCR2 (1.00) | CCR2 | |
| SCHEMBL8458456 | 0.76 | CCR2 (0.65) | CCR2 | |
| SCHEMBL6770077 | 0.76 | CCR2 (0.65) | CCR2 | |
| SCHEMBL6768880 | 0.75 | CCR2 (0.64) | CCR2CCR5 | |
| SCHEMBL6770934 | 0.75 | CCR2 (1.00) | CCR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686353-B1 | PREVENTING BLOOD MONOCYTES AND LYMPHOCYTES FROM INFILTRATING TISSUE | TEIJIN INTELLECTUAL PROPERTY CENTER LIMITED (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-0914319-B1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| EP-0914319-A1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LIMITED (JP) | 1999-05-12 | — | — | EP | disclosed |
| WO-1997044329-A9 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | — | 1998-03-12 | — | — | WO | disclosed |
| WO-1997044329-A1 | DIARYLALKYL CYCLIC DIAMINE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | TEIJIN LIMITED (JP) | 1997-11-27 | — | — | WO | disclosed |