Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 2/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721276 | 0.81 | ESR1 (0.44) | ARMAOBERN1TP53MAPT | |
| SCHEMBL9721255 | 0.75 | ERN1 (0.39) | ALBARLDHALDHBERN1 | |
| SCHEMBL9721231 | 0.75 | SENP1 (0.44) | ALBMAOBLDHALDHBTP53 | |
| SCHEMBL9721301 | 0.73 | ERN1 (0.47) | ALBLDHALDHBERN1CA12 | |
| SCHEMBL9721314 | 0.72 | ERN1 (0.39) | ALBARLDHALDHBERN1 | |
| SCHEMBL9721316 | 0.72 | ERN1 (0.39) | ALBARLDHALDHBERN1 | |
| SCHEMBL17166195 | 0.71 | CYP2A6 (0.59) | ALBMAOBALPGMAPTALDH1A1 | |
| SCHEMBL9721353 | 0.71 | PADI4 (0.60) | ARERN1MAPTPADI4ALDH1A1 | |
| SCHEMBL9721268 | 0.71 | NOX4 (0.42) | ERN1TP53MAPTCSNK2A2CSNK2B | |
| SCHEMBL17166196 | 0.69 | CYP2A6 (0.56) | ALBALPGMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | claimed |
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | disclosed |
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | disclosed |