Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721316 | 0.91 | ERN1 (0.39) | ERN1HSD17B1HSD17B2ESR1CYP3A4 | |
| SCHEMBL9721255 | 0.87 | ERN1 (0.39) | ERN1ESR1CYP3A4MAPTMEN1 | |
| SCHEMBL9721268 | 0.83 | NOX4 (0.42) | ERN1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL9721292 | 0.77 | HSD17B1 (0.41) | ESR2HSD17B1HSD17B2ESR1CYP3A4 | |
| SCHEMBL9721275 | 0.74 | TLR8 (0.40) | ERN1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL9721289 | 0.72 | ALB (0.49) | ERN1MAPTTP53LDHAALDH1A1 | |
| SCHEMBL9721269 | 0.68 | SENP1 (0.36) | HSD17B1HSD17B2CYP3A4MAPTKDM4E | |
| SCHEMBL9721276 | 0.68 | ESR1 (0.44) | ERN1ESR2ESR1CYP3A4MAPT | |
| SCHEMBL9721287 | 0.68 | AKR1B1 (0.40) | ERN1ESR1CYP3A4MAPTMEN1 | |
| SCHEMBL9721322 | 0.68 | CYP3A4 (0.40) | ERN1ESR1CYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | claimed |
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | disclosed |