Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 6/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721314 | 0.83 | ERN1 (0.39) | KDM4ERAB9APADI4ERN1MEN1 | |
| SCHEMBL9721316 | 0.83 | ERN1 (0.39) | KDM4ERAB9APADI4ERN1MEN1 | |
| SCHEMBL9721255 | 0.78 | ERN1 (0.39) | KDM4EPTGS2RAB9APADI4ERN1 | |
| SCHEMBL9721276 | 0.73 | ESR1 (0.44) | NOX4KDM4ERAB9APADI4ERN1 | |
| SCHEMBL9721232 | 0.71 | APP (0.46) | APPALOX5KDM4EPTGS2RAB9A | |
| SCHEMBL9721289 | 0.71 | ALB (0.49) | PADI4ERN1ALDH1A1TP53MAPT | |
| SCHEMBL9721312 | 0.70 | MAPK8 (0.34) | KDM4ERAB9APADI4ERN1MEN1 | |
| SCHEMBL9721353 | 0.67 | PADI4 (0.60) | KDM4EPADI4ERN1MEN1ALDH1A1 | |
| SCHEMBL12322571 | 0.65 | APP (0.62) | NOX4APPALOX5MAPT | |
| SCHEMBL6638868 | 0.65 | ERN1 (0.67) | APPERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | claimed |
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | claimed |
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | disclosed |