Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.33 |
| ▸ | RGS17 | Q9UGC6 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721380 | 0.80 | CYP3A4 (0.39) | KDM4EMEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL9721310 | 0.79 | CYP3A4 (0.35) | KDM4EMEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL9721303 | 0.70 | SELL (0.37) | MAPK8KDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL9721278 | 0.70 | KDM4E (0.40) | MAPK8KDM4EMEN1ALDH1A1CYP3A4 | |
| SCHEMBL9721268 | 0.70 | NOX4 (0.42) | KDM4EMEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL10454966 | 0.70 | CYP3A4 (0.35) | KDM4EMEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL9721287 | 0.70 | AKR1B1 (0.40) | KDM4EMEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL9721322 | 0.70 | CYP3A4 (0.40) | KDM4EMEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL9721316 | 0.65 | ERN1 (0.39) | KDM4EMEN1ALDH1A1CYP3A4MAPT | |
| SCHEMBL31648926 | 0.63 | CYP3A4 (0.48) | KDM4ECYP3A4MAPTERN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | claimed |
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | claimed |
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | disclosed |
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | disclosed |