Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721303 | 0.87 | SELL (0.37) | CYP3A4SENP1 | |
| SCHEMBL9721344 | 0.79 | CA1 (0.38) | ACHE | |
| SCHEMBL9721281 | 0.72 | CA1 (0.37) | ACHESENP1 | |
| SCHEMBL9721311 | 0.70 | MAOA (0.36) | ACHEMAOACYP3A4ABCB1 | |
| SCHEMBL9721235 | 0.68 | ERN1 (0.41) | MAOA | |
| SCHEMBL13695148 | 0.68 | ACHE (0.65) | ACHECYP3A4 | |
| SCHEMBL25575178 | 0.65 | SENP1 (0.42) | ACHEMAOACYP3A4SENP1 | |
| SCHEMBL9721269 | 0.65 | SENP1 (0.36) | ACHECYP3A4SENP1 | |
| SCHEMBL31545510 | 0.64 | TRPA1 (0.46) | ACHEMAOACYP3A4 | |
| SCHEMBL3195155 | 0.63 | ACHE (0.56) | ACHEMAOACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | claimed |
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | claimed |
| US-5112869-A | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-05-12 | — | — | US | disclosed |
| WO-1990011988-A1 | SUBSTITUTED 1-PHENYLNAPHTHALENES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-10-18 | — | — | WO | disclosed |