Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722220 | 0.88 | DRD2 (0.43) | DRD2DRD4SIGMAR1HTR2AHTR1A | |
| SCHEMBL9722378 | 0.78 | DRD2 (0.49) | DRD2DRD4SIGMAR1HTR2AHTR1A | |
| SCHEMBL2976277 | 0.71 | GBA1 (0.52) | DRD2DRD4SIGMAR1HTR2A | |
| SCHEMBL20850591 | 0.68 | TNKS (0.49) | DRD2DRD4SIGMAR1HTR2AHTR1A | |
| SCHEMBL14046594 | 0.68 | SORD (0.54) | DRD2HTR2AHTR1A | |
| SCHEMBL3556933 | 0.68 | KDM4E (0.52) | DRD2DRD4SIGMAR1HTR1AKDM4E | |
| SCHEMBL9722260 | 0.67 | DRD2 (0.50) | DRD2HTR2AHTR1A | |
| SCHEMBL9722264 | 0.67 | DRD2 (0.50) | DRD2HTR2AHTR1A | |
| SCHEMBL9722266 | 0.67 | HTR2A (0.49) | DRD2HTR2AHTR1A | |
| SCHEMBL7882827 | 0.66 | DRD2 (0.62) | DRD2DRD4SIGMAR1HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |