Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474882 | 0.81 | SIGMAR1 (0.52) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL1484564 | 0.75 | LMNA (0.54) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL28644066 | 0.74 | LMNA (0.46) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| Hydrochloric Acid SCHEMBL9079605 | 0.73 | LMNA (0.52) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL1006036 | 0.70 | LMNA (0.54) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL14859797 | 0.70 | LMNA (0.43) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL28729461 | 0.70 | BPTF (0.43) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL9620435 | 0.70 | LMNA (0.43) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL576454 | 0.69 | LMNA (0.67) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL164538 | 0.69 | LMNA (0.67) | LMNASIGMAR1HTR3EHTR3BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510439-A1 | Compositions of polyarylene sulphides, glass fibres and melamine resins | BAYER AG (DE) | 1992-10-28 | — | — | EP | disclosed |
| EP-0502358-A1 | Composition of polyarylene sulphides, melamine resins and rubbers | BAYER AG (DE) | 1992-09-09 | — | — | EP | disclosed |
| US-3966727-A | Manufacture of phthalo-bis-guanamines | BASF AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |