Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620435 | 0.95 | LMNA (0.43) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL474882 | 0.87 | SIGMAR1 (0.52) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL28500287 | 0.78 | HTR6 (0.35) | LMNAMAPK1HSD17B10MAPTPOLB | |
| SCHEMBL4116845 | 0.76 | AKR1C3 (0.37) | LMNAHSD17B10MAPTMEN1KMT2A | |
| SCHEMBL1006036 | 0.76 | LMNA (0.54) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL904660 | 0.75 | DRD4 (0.57) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| Bromide SCHEMBL19272502 | 0.74 | LMNA (0.52) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| Hydrochloric Acid SCHEMBL14334304 | 0.74 | LMNA (0.52) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL28644066 | 0.74 | LMNA (0.46) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL10966975 | 0.73 | MAPT (0.49) | LMNASIGMAR1HTR3EHTR3BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559459-B2 | Aromatic heterocyclic derivative, and organic electroluminescent element, illumination device, and display device using aromatic heterocyclic derivative | MERCK PATENT GMBH (DE) | 2026-02-24 | — | — | US | disclosed |
| CN-118894842-A | Organic compound, organic photoelectric element containing same and application | 上海蓝屏医疗科技有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-117304197-A | Electron transport material and organic electroluminescent device comprising same | 上海和辉光电股份有限公司 | 2023-12-29 | — | — | CN | disclosed |
| EP-3538623-B1 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | MERCK PATENT GMBH (DE) | 2023-12-20 | — | — | EP | disclosed |
| US-20230354701-A1 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | MERCK PATENT GMBH (DE) | 2023-11-02 | — | — | US | disclosed |
| EP-4271163-A2 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | Merck Patent GmbH (DE) | 2023-11-01 | — | — | EP | disclosed |
| EP-4271160-A2 | AROMATIC HETEROCYCLIC DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE USING AROMATIC HETEROCYCLIC DERIVATIVE | Merck Patent GmbH (DE) | 2023-11-01 | — | — | EP | disclosed |
| US-11711976-B2 | Compounds with an acceptor and a donor group | MERCK PATENT GMBH (DE) | 2023-07-25 | — | — | US | disclosed |
| EP-3257850-B1 | AROMATIC HETEROCYCLIC DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE USING AROMATIC HETEROCYCLIC DERIVATIVE | MERCK PATENT GMBH (DE) | 2023-06-28 | — | — | EP | disclosed |
| CN-115894446-A | Azaspiro-bifluorene compound, preparation containing azaspirobifluorene compound, organic light-emitting element and display or lighting device | 上海弗屈尔光电科技有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-20180037546-A1 | AROMATIC HETEROCYCLIC DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE USING AROMATIC HETEROCYCLIC DERIVATIVE | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| CN-105001229-B | A kind of organic electroluminescent compounds and its device with spiro structure | 上海道亦化工科技有限公司 | 2018-02-02 | — | — | CN | disclosed |
| EP-3257850-A1 | AROMATIC HETEROCYCLIC DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE USING AROMATIC HETEROCYCLIC DERIVATIVE | Konica Minolta, Inc. (JP) | 2017-12-20 | — | — | EP | disclosed |
| US-20170309834-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-10-26 | — | — | US | disclosed |
| US-20160260911-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-09-08 | — | — | US | disclosed |
| US-20160226003-A1 | HETEROCYCLIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| EP-3044285-A1 | HETEROCYCLIC COMPOUNDS | Merck Patent GmbH (DE) | 2016-07-20 | — | — | EP | disclosed |
| US-9379330-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| WO-2015036078-A1 | HETEROCYCLIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2015-03-19 | — | — | WO | disclosed |
| US-20130092922-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559459-B2 | Aromatic heterocyclic derivative, and organic electroluminescent element, illumination device, and display device using aromatic heterocyclic derivative | NR2E3, CDYL, TYR | LMNA 1625/4885SIGMAR1 1224/4885HTR3E 1016/4885 |
| US-20160226003-A1 | HETEROCYCLIC COMPOUNDS | ERCC1, VDAC2, NES | LMNA 2484/4885SIGMAR1 2731/4885HTR3E 1142/4885 |
| US-20180037546-A1 | AROMATIC HETEROCYCLIC DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT, ILLUMINATION DEVICE, AND DISPLAY DEVICE USING AROMATIC HETEROCYCLIC DERIVATIVE | NLRP3, TYR, NLRP1 | LMNA 2200/4885SIGMAR1 3591/4885HTR3E 265/4885 |
| US-20170309834-A1 | MATERIALS FOR ELECTRONIC DEVICES | SCO2, AOC2, HCN2 | LMNA 2787/4885SIGMAR1 3513/4885HTR3E 4115/4885 |
| US-11711976-B2 | Compounds with an acceptor and a donor group | NQO1, ICMT, NUDT1 | LMNA 4314/4885SIGMAR1 3002/4885HTR3E 1924/4885 |
| US-20160260911-A1 | MATERIALS FOR ELECTRONIC DEVICES | SCO2, AOC2, HCN2 | LMNA 2787/4885SIGMAR1 3513/4885HTR3E 4115/4885 |
| US-20230354701-A1 | COMPOUNDS WITH AN ACCEPTOR AND A DONOR GROUP | NQO1, ICMT, NUDT1 | LMNA 4314/4885SIGMAR1 3002/4885HTR3E 1924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.