SCHEMBL9723156

SCHEMBL9723156

CCOC(=O)C1(C(=O)OCC)OC1C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
LMNA P02545 4/20 0.39
KDM4E B2RXH2 2/20 0.39
HSD17B10 Q99714 2/20 0.39
GAA P10253 3/20 0.37
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
ATM Q13315 1/20 0.37
POLB P06746 2/20 0.35
TRPA1 O75762 1/20 0.34
HTT P42858 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9723178 0.90 LMNA (0.36) ALDH1A1LMNAKDM4EHSD17B10GAA
SCHEMBL11435161 0.88 ALOX15 (0.41) ALDH1A1LMNAKDM4EHSD17B10GAA
SCHEMBL7061157 0.80 ALDH1A1 (0.39) ALDH1A1LMNAKDM4EHSD17B10GAA
SCHEMBL8473845 0.75 LMNA (0.35) ALDH1A1LMNAKDM4EHSD17B10GAA
SCHEMBL31536690 0.75 POLB (0.39) ALDH1A1LMNAKDM4EHSD17B10GAA
SCHEMBL18482793 0.72 PPM1B (0.37) ALDH1A1LMNAKDM4EHSD17B10GAA
SCHEMBL31536683 0.72 ATM (0.38) ALDH1A1LMNAKDM4EHSD17B10GAA
SCHEMBL20468466 0.72 ATM (0.32) LMNAATMPOLBMEN1KMT2A
SCHEMBL372116 0.71 ALDH1A1 (0.43) ALDH1A1LMNAKDM4EHSD17B10GAA
SCHEMBL372115 0.71 ALDH1A1 (0.43) ALDH1A1LMNAKDM4EHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5123951-A Ethylene response inducing agent and malonic acid derivative RHONE-POULENC NEDERLAND B.V. (NL) 1992-06-23 US disclosed