Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723156 | 0.75 | ALDH1A1 (0.40) | POLBLMNAALDH1A1HSD17B10ATM | |
| SCHEMBL31536555 | 0.75 | ALDH1A1 (0.42) | POLBLMNAALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL14507330 | 0.72 | LMNA (0.37) | POLBLMNAALDH1A1HSD17B10ATM | |
| SCHEMBL18346711 | 0.71 | ALOX15 (0.42) | POLBLMNAALDH1A1HSD17B10ATM | |
| SCHEMBL5116398 | 0.71 | ALOX15 (0.42) | POLBLMNAALDH1A1HSD17B10ATM | |
| SCHEMBL9723178 | 0.71 | LMNA (0.36) | POLBLMNAALDH1A1HSD17B10ATM | |
| SCHEMBL20348810 | 0.71 | LMNA (0.39) | POLBLMNAALDH1A1HSD17B10ATM | |
| SCHEMBL20364186 | 0.69 | F10 (0.40) | POLBLMNAALDH1A1HSD17B10ATM | |
| SCHEMBL5480009 | 0.69 | ALDH1A1 (0.39) | POLBLMNAALDH1A1HSD17B10ATM | |
| SCHEMBL10602801 | 0.69 | ALDH1A1 (0.39) | POLBLMNAALDH1A1HSD17B10ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025080946-A2 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-04-17 | — | — | WO | disclosed |