Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723156 | 0.90 | ALDH1A1 (0.40) | LMNAKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL11435161 | 0.82 | ALOX15 (0.41) | LMNAKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL7061157 | 0.75 | ALDH1A1 (0.39) | LMNAKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL38663307 | 0.74 | SMN1; SMN2 (0.32) | GAAATMSMN1; SMN2PPM1BPTPN1 | |
| SCHEMBL4401205 | 0.71 | ALDH1A1 (0.39) | LMNAKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL12181098 | 0.71 | ALDH1A1 (0.39) | LMNAKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL8473845 | 0.71 | LMNA (0.35) | LMNAKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL31536690 | 0.71 | POLB (0.39) | LMNAKDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL57715 | 0.68 | OPRM1 (0.49) | GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL18482793 | 0.68 | PPM1B (0.37) | LMNAKDM4EALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5123951-A | Ethylene response inducing agent and malonic acid derivative | RHONE-POULENC NEDERLAND B.V. (NL) | 1992-06-23 | — | — | US | disclosed |