Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279664 | 0.82 | ALDH1A1 (0.39) | KDM4E | |
| SCHEMBL9738923 | 0.72 | LMNA (0.38) | BACE1MAOAMAOBPTPN1CDC25B | |
| SCHEMBL3720449 | 0.72 | BACE1 (0.41) | BACE1MAOAMAOBCFTRGOPC | |
| SCHEMBL461353 | 0.71 | MAOA (0.31) | MAOAMAOB | |
| SCHEMBL9763428 | 0.69 | BACE1 (0.38) | BACE1MAOAMAOBCFTRGOPC | |
| SCHEMBL8191410 | 0.69 | BACE1 (0.44) | BACE1MAOAMAOBCFTRGOPC | |
| SCHEMBL19814894 | 0.68 | KDM4E (0.34) | MAOAMAOBPTPN1KDM4EKMO | |
| SCHEMBL7707431 | 0.67 | MAOA (0.31) | MAOAMAOB | |
| SCHEMBL6407297 | 0.67 | CTH (0.31) | MAOAMAOB | |
| SCHEMBL11768483 | 0.66 | SRD5A2 (0.47) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114613-A | High-speed responsive, stable films; controlling the mesomorphic state and temperature | CANON KABUSHIKI KAISHA (JP) | 1992-05-19 | — | — | US | disclosed |
| US-4882085-A | Lactic acid derivative and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1989-11-21 | — | — | US | disclosed |