Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723934 | 0.91 | ALDH1A1 (0.52) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL9723937 | 0.78 | CSF1R (0.45) | MAPTRAB9AKMT2AMAPK1MEN1 | |
| SCHEMBL9271308 | 0.74 | MAPT (0.61) | MAPTRAB9AKMT2AMAPK1NPC1 | |
| SCHEMBL29280508 | 0.72 | PPARG (0.54) | MAPTRAB9AKMT2AMAPK1NPC1 | |
| SCHEMBL9265847 | 0.72 | MEN1 (0.47) | MAPTRAB9AKMT2AMAPK1NPC1 | |
| SCHEMBL9723924 | 0.70 | PPARG (0.44) | MAPTRAB9AKMT2AMAPK1NPC1 | |
| SCHEMBL8188082 | 0.69 | RXFP1 (0.39) | MAPTRXFP1KDM4EALDH1A1TSHR | |
| SCHEMBL5085480 | 0.66 | PPARG (0.71) | MAPTRAB9AKMT2AMAPK1NPSR1 | |
| SCHEMBL9265791 | 0.66 | ALDH1A1 (0.53) | MAPTRAB9AKMT2AMAPK1NPC1 | |
| SCHEMBL19248489 | 0.66 | KMT2A (0.56) | MAPTRAB9AKMT2AMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089504-A | SUBSTITUTED 4-AMINOQUINOLINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-02-18 | — | — | US | disclosed |