Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401274 | 0.88 | HSD17B1 (0.49) | HSD17B1HSD17B2MAPTATML3MBTL1 | |
| SCHEMBL9724133 | 0.79 | USP7 (0.60) | HSD17B1HSD17B2L3MBTL1KDM4ESLC6A2 | |
| SCHEMBL7826596 | 0.78 | USP47 (0.52) | HSD17B1HSD17B2MAPTL3MBTL1KDM4E | |
| SCHEMBL2682523 | 0.77 | USP47 (0.70) | MAPTL3MBTL1ALDH1A1HPGDUSP7 | |
| SCHEMBL9724087 | 0.75 | NOTUM (0.40) | MAPTKDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL216900 | 0.74 | HSD17B1 (0.54) | HSD17B1HSD17B2MAPTL3MBTL1KDM4E | |
| SCHEMBL11069105 | 0.74 | HPGD (0.60) | ATML3MBTL1KDM4ESLC6A2SLC6A4 | |
| SCHEMBL9724102 | 0.73 | ATM (0.46) | MAPTATML3MBTL1KDM4ESLC6A2 | |
| SCHEMBL9724108 | 0.73 | ALOX5 (0.48) | ATML3MBTL1KDM4EGAA | |
| SCHEMBL9724116 | 0.72 | ALDH1A1 (0.40) | MAPTATML3MBTL1KDM4ESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |