Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724161 | 0.81 | KDM4E (0.46) | ATML3MBTL1KDM4EHPGDSLC6A4 | |
| SCHEMBL9724108 | 0.77 | ALOX5 (0.48) | ATML3MBTL1KDM4ELMNAGAA | |
| SCHEMBL9724116 | 0.74 | ALDH1A1 (0.40) | ATML3MBTL1KDM4EXBP1HPGD | |
| SCHEMBL9724101 | 0.73 | HSD17B1 (0.48) | ATML3MBTL1KDM4EXBP1HPGD | |
| SCHEMBL9724106 | 0.72 | KDM4E (0.38) | ATML3MBTL1KDM4EXBP1HPGD | |
| SCHEMBL25863567 | 0.72 | PNMT (0.51) | ATML3MBTL1SLC6A4MAPTNPSR1 | |
| SCHEMBL11401274 | 0.71 | HSD17B1 (0.49) | ATML3MBTL1KDM4EXBP1HPGD | |
| SCHEMBL9724087 | 0.69 | NOTUM (0.40) | KDM4EXBP1HPGDSLC6A4SLC6A2 | |
| SCHEMBL30688819 | 0.69 | XBP1 (0.57) | ATML3MBTL1KDM4EXBP1HPGD | |
| SCHEMBL8863159 | 0.69 | XBP1 (0.57) | ATML3MBTL1KDM4EXBP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |