Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724102 | 0.81 | ATM (0.46) | KDM4EL3MBTL1POLBSLC6A2SLC6A4 | |
| SCHEMBL9724112 | 0.75 | ALOX5 (0.53) | — | |
| SCHEMBL9724100 | 0.72 | KDM4E (0.48) | KDM4EPKML3MBTL1USP7TP53 | |
| SCHEMBL9724133 | 0.70 | USP7 (0.60) | KDM4EPKML3MBTL1USP7POLB | |
| SCHEMBL9724167 | 0.70 | KDM4E (0.46) | KDM4EPKML3MBTL1USP7TP53 | |
| SCHEMBL12330147 | 0.69 | COASY (0.47) | HPGDMEN1KMT2AALDH1A1GPR139 | |
| SCHEMBL11392906 | 0.69 | HSD17B1 (0.52) | KDM4EPKML3MBTL1USP7TP53 | |
| SCHEMBL11521691 | 0.68 | L3MBTL1 (0.68) | KDM4EPKML3MBTL1USP7TP53 | |
| SCHEMBL9724080 | 0.67 | KDM4E (0.51) | KDM4EPKML3MBTL1USP7POLB | |
| SCHEMBL2282611 | 0.66 | POLB (0.56) | KDM4EPKML3MBTL1POLBSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |