Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362496 | 0.89 | MMP2 (0.47) | ALDH1A1MAPTHPGDMAOBTDP1 | |
| SCHEMBL10362664 | 0.89 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDMAOBTDP1 | |
| SCHEMBL10667279 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDMAOBTDP1 | |
| SCHEMBL10362708 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDMAOBTDP1 | |
| SCHEMBL8437058 | 0.87 | NPBWR1 (0.38) | ALDH1A1MAPTHPGDMAOBTDP1 | |
| SCHEMBL8434757 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MAPTHPGDMAOBTDP1 | |
| SCHEMBL9199587 | 0.84 | RAB9A (0.46) | RAB9ANPC1ALDH1A1MAPTHPGD | |
| SCHEMBL9728072 | 0.84 | RAB9A (0.46) | RAB9ANPC1ALDH1A1MAPTHPGD | |
| SCHEMBL9208996 | 0.84 | RAB9A (0.46) | RAB9ANPC1ALDH1A1MAPTHPGD | |
| SCHEMBL8439607 | 0.83 | SMN1; SMN2 (0.39) | ALDH1A1MAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102997-A | Antibiotics | SANKYO COMPANY LIMITED (JP) | 1992-04-07 | — | — | US | disclosed |
| US-4740507-A | Carbapenem compounds and use | SANKYO COMPANY LIMITED (JP) | 1988-04-26 | — | — | US | disclosed |
| EP-0186525-A1 | Carbapenem compounds, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |