Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22408381 | 0.82 | ATM (0.58) | ATMHSP90AA1CYP2C19CYP3A4ALOX12 | |
| SCHEMBL9724819 | 0.79 | MME (0.58) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9724808 | 0.79 | MEN1 (0.53) | ATMALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL5037571 | 0.79 | MAPK1 (0.63) | CYP2C19CYP3A4CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL9678826 | 0.78 | CTSS (0.59) | ATMHSP90AA1L3MBTL1 | |
| SCHEMBL9724970 | 0.77 | MAPT (0.55) | CYP1A2ALDH1A1MAPTPOLBMEN1 | |
| Hydrochloric Acid SCHEMBL22408313 | 0.76 | ATM (0.46) | ATMHSP90AA1CYP2C19CYP3A4ALOX12 | |
| SCHEMBL9851086 | 0.76 | TDP1 (0.47) | ATMHSP90AA1CYP2C19CYP3A4ALOX12 | |
| SCHEMBL9724829 | 0.74 | BACE1 (0.54) | MAPTMEN1KMT2A | |
| SCHEMBL9724959 | 0.74 | GAA (0.55) | L3MBTL1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |